Pre-Transplant Gut Colonization with Intrinsically Vancomycin-Resistant Enterococci (E. Gallinarum and E. Casseliflavus) and Outcomes of Allogeneic Hematopoietic Cell Transplantation

• Pre-transplant iVRE gut colonization is uncommon and with unknown clinical impact.• OS was higher among patients with vs. without pre-transplant iVRE gut colonization.• Putative metabolomes differentiated iVRE from E. faecalis/faecium.• Unique iVRE metabolomes may create a healthier gut mi crobiome in colonized patients.

Source: Biology of Blood and Marrow Transplantation - February 3, 2018 Category: Hematology Authors: Armin Rashidi, Maryam Ebadi, Robin R. Shields-Cutler, Todd E. DeFor, Gabriel A. Al-Ghalith, Patricia Ferrieri, Jo-Anne H. Young, Gary M. Dunny, Dan Knights, Daniel J. Weisdorf Source Type: research