Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ

Tumour-infiltrating lymphocytes (TILs) have been demonstrated to significantly influence prognosis and response to therapy of invasive breast cancer (IBC). Thus, it has been suggested that TIL density or/and i...
Source: BMC Cancer - Category: Cancer & Oncology Authors: Tags: Research article Source Type: research

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This study could significantly change the way we approach breast cancer screening." MRI is much more sensitive than mammography, "  saidGreg Karczmar, PhD, professor of radiology at the University of Chicago. " It can find invasive breast cancers sooner than mammograms and it can rule out abnormalities that appear suspicious on a mammogram. Unfortunately, MRI is much too expensive for routine screening. "
Source: radRounds - Category: Radiology Authors: Source Type: blogs
Conclusion: The expression of CAF-related proteins in stromal cells of DCIS varies according to molecular subtype and stromal type.Pathobiology
Source: Pathobiology - Category: Pathology Source Type: research
Authors: Liu W, Wu J, Shi G, Yue X, Liu D, Zhang Q Abstract Protocadherin-10 (PCDH10) is a tumor suppressor gene. Its expression level is downregulated by promoter methylation in certain types of human tumors. The aim of the present study was to examine the expression level and promoter methylation status of PCDH10 in breast cancer cells and to evaluate the association of PCDH10 methylation and tumor progression and prognosis. MethyLight was used to detect the methylation status of PCDH10 in breast cancer tissues and healthy breast tissues. Reverse transcription-quantitative polymerase chain reaction was used to as...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Publication date: October 2018Source: Seminars in Cancer Biology, Volume 52, Part 2Author(s): Maria Vittoria Dieci, Nina Radosevic-Robin, Susan Fineberg, Gert van den Eynden, Nils Ternes, Frederique Penault-Llorca, Giancarlo Pruneri, Timothy M. D’Alfonso, Sandra Demaria, Carlos Castaneda, Joselyn Sanchez, Sunil Badve, Stefan Michiels, Veerle Bossuyt, Federico Rojo, Baljit Singh, Torsten Nielsen, Giuseppe Viale, Seong-Rim Kim, Stephen HewittAbstractMorphological evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer is gaining momentum as evidence strengthens the clinical relevance of this immunological ...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Condition:   Outcome of Breast Cancer Intervention:   Other: None intervention Sponsor:   Omphis Foundation Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Outcome of Breast Cancer Intervention:   Other: None intervention Sponsor:   Omphis Foundation Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Outcome of Breast Cancer Intervention:   Other: None intervention Sponsor:   Omphis Foundation Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Outcome of Breast Cancer Intervention:   Other: None intervention Sponsor:   Omphis Foundation Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Outcome of Breast Cancer Intervention:   Other: None intervention Sponsor:   Omphis Foundation Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Outcome of Breast Cancer Intervention:   Other: None intervention Sponsor:   Omphis Foundation Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Breast Cancer | Breast Carcinoma | Cancer | Cancer & Oncology | Carcinoma | Carcinoma in Situ | DCIS (Ductal Carcinoma in Situ) | Ductal Carcinoma