[Stereocontrolled Total Synthesis of Biologically Active Natural Products].

[Stereocontrolled Total Synthesis of Biologically Active Natural Products].
Yakugaku Zasshi. 2018;138(2):191-209
Authors: Hatakeyama S
Abstract
　This review article describes the total syntheses of englerin A, ophiodilactones A and B, marinomycin A, N-methylwelwitindolinone C isothiocyanate, tirandamycins A-D, and tirandalydigin, which possess intriguing biological activities and challenging structures with characteristic ring systems. The focus is on the synthetic methodologies that lead to the highly stereocontrolled assembly of these natural products.
PMID: 29386433 [PubMed - in process]

Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - February 3, 2018 Category: Drugs & Pharmacology Authors: Hatakeyama S Tags: Yakugaku Zasshi Source Type: research