Disrupted salience processing involved in motivational deficits for real-life activities in patients with schizophrenia

This study aimed to identify impairment of the salience network that underlies motivational deficits seen in patients with schizophrenia in real-life situations. During the functional magnetic resonance imaging scan, 20 patients with schizophrenia and 20 normal controls performed a task mimicking real-life situations, in which an avatar proposed participation in a daily activity with either an intrinsic or extrinsic reward.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research