Can smoking marijuana cause meningitis?

Cryptococcus neoformans ( 2.5 out of 5 stars Cryptococcal meningitis in a daily cannabis smoker without evidence of immunodeficiency. Shapiro BB et al. BMJ Case Rep 2018 Jan 26 [Epub ahead of print] Abstract Can smoking marijuana cause meningitis? The question is not unreasonable. A wide range of pathogenic fungi — including Aspergillus and various Cryptococcus species — have been isolated from dispensary-grade medical marijuana samples. Concern that these pathogens could cause pneumonia or central nervous system infections has focussed on those with immunodeficiency, such as HIV and organ transplant patients. This case report describes at 48-year-old California woman who presented to hospital with a “2-month history of progressive fatigue, dizziness, memory impairment, ataxia, and left-sided numbness and weakness.” She had a state medical marijuana card and reported smoking multiple “blunts” daily for the previous 35 years. Tests were negative for HIV. Several days after admission, the patient developed lethargy and increasingly altered mental status. A lumbar puncture was performed, revealing increased white cell and protein with markedly low glucose (
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical cannabis cryptococcus fungal infection marijuana meningitis Source Type: news

Related Links:

A new study shows racial and socioeconomic disparities in outcome for MI, heart failure, and pneumonia, but findings suggest they stem not from level of care but larger systemic causes.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Cardiology News Source Type: news
In this study, isolated ssDNA aptamers by ST-SELEX were used for detection of SEA via apta-Real time PCR (apta-qPCR). After in silico analysis of SEA protein with SEE and finding the specific region on the surface of protein, ST-SELEX was carried out in two steps (classical SELEX and Second SELEX). Finally, after isolating high specific aptamers, the apta-qPCR was used for the detection of the SEA. In this technique, poly-clonal antibody against SEA was immobilized on protein G sepharose beads (Ab-PGs). Then, the SEA protein was captured by poly clonal antibody as the target that immobilized on sepharose beads. The isolate...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Authors: Czemerska M, Robak T, Wierzbowska A Abstract INTRODUCTION: Acute myeloid leukemia (AML) remains a poor prognosis hematological malignancy. The introduction of aggressive chemotherapy with allogeneic stem cell transplantation has resulted in improved clinical outcomes in younger patients. However, the treatment results in unfit elderly AML population remain disappointing. New strategies should be introduced to improve the prognosis in this group of patients. Areas covered: This review presents and discusses the mechanism of action, safety and efficacy of sapacitabine in AML patients. Expert opinion: Sapacit...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Authors: Daniels LM, Kufel WD Abstract INTRODUCTION: Clostridium difficile infection (CDI) has become a significant healthcare-associated infection and is strongly associated with antibiotic use. Practice guidelines have recently been revised incorporating updated recommendations for diagnosis, treatment, and prevention. Areas Covered: This review discusses updated aspects of CDI management. New and emerging pharmacologic options for treatment and prevention are reviewed. Expert opinion: Metronidazole is associated with lower rates of treatment success compared to vancomycin and should no longer be used as primary ...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
This study was conducted to determine the contact toxicity and biochemical effects of itol A on the Nilaparvata lugens. After macropterous females of N. lugens were exposed to itol A from 0.5 to 24 h, the mortality and poisoning symptoms were measured. Effects of itol A on the major enzymes activity and oxidative stress level were assessed in dose-response (with LD10-LD70 at 24 h) and time-course (with LD50 at 0.5–24 h) experiments for the potential toxicity mechanisms. Based on the results, the mortality of N. lugens showed significant dose- and time-dependent effects, with the 24-h LD50 value was 0.58 μg...
Source: Pesticide Biochemistry and Physiology - Category: Biochemistry Source Type: research
ConclusionsTransfusions are prevalent in the perioperative period after pediatric kidney transplantation. Lower pre-transplant hemoglobin increases the risk of transfusion. Graft function predicts hemoglobin levels at 3  months.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsAlthough we do not have a control group, we may speculate that patients who received treatment returned to a “standard” condition possibly improving final outcome. Protocol biopsies are a powerful diagnostic tool for the management of pediatric renal transplant recipients. In view of the lack of evidence that biopsies taken 5 years after transplantation lead to any therapeutic change, their use should be reconsidered.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
This study aimed to evaluate plasma concentrations of leptin and total ghrelin in children with chronic kidney disease (CKD) and assess their roles in protein-energy wasting (PEW).MethodsThis study consisted of three different CKD populations [CKD group (20 patients with non-dialysis CKD), dialysis group (39 patients on dialysis), and kidney transplant (KTx) group (35 KTx recipients)] and control group (18 healthy children). Plasma leptin and total ghrelin levels were measured. Multi-frequency bioimpedance analysis was used for the assessment of fat and lean mass. PEW was defined using criteria including body mass, muscle ...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
CONCLUSION: The C. cyminum L. and C. sativum L EOs could be good alternative to protect foods. PMID: 30221882 [PubMed - in process]
Source: Pakistan Journal of Biological Sciences: PJBS - Category: Biomedical Science Authors: Tags: Pak J Biol Sci Source Type: research
Authors: Peled Y, Freimark D, Har-Zahav Y, Nachum E, Kogan A, Kassif Y, Lavee J Abstract BACKGROUND: Heart transplantation (HT) is the treatment of choice for patients with end-stage heart failure. The HT unit at the Sheba Medical Center is the largest of its kind in Israel. OBJECTIVES: To evaluate the experience of HT at a single center, assess trends over 3 decades, and correlate with worldwide data. METHODS: Between 1990 and 2017, we reviewed all 285  adult HT patients. Patients were grouped by year of HT: 1990-1999 (decade 1), 2000-2009 (decade 2), and 2010-2017 (decade 3). RESULTS: The percent...
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
More News: Allergy & Immunology | Aspergillus | Ataxia | Fungal Infections | Hospitals | Lumbar Puncture | Lung Transplant | Men | Meningitis | Pneumonia | Poisoning | Smokers | Toxicology | Transplants | Wikis