GSE108871 Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments

Contributors : Elizabeth Brunk ; Roger L Chang ; Jing Xia ; Hooman Hefzi ; James T Yurkovich ; Donghyuk Kim ; Evan Buckmiller ; Harris Wang ; Byung-Kwan Cho ; Chen Yang ; Bernhard O Palsson ; George M Church ; Nathan E LewisSeries Type : Expression profiling by arrayOrganism : Escherichia coliE. coli K-12 MG1655 was grown on M9 minimal media supplemented with 0.2% w/v glucose, fructose, or acetate. The goal of this study was to determine differentially expressed genes in the different media conditions.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Escherichia coli Source Type: research

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Publication date: Available online 20 July 2018Source: Journal of EthnopharmacologyAuthor(s): Dagmar Brislinger, Christine Daxböck, Eva Roßmanith, Manuela Stückler, Ingrid Lang, Dieter FalkenhagenAbstractEthnopharmacological relevanceSepsis is a systemic inflammatory response of the body to a severe infection or massive tissue injury. Despite intensive research, sepsis continues to have a high mortality rate and successful treatment options are strongly needed. Bai Hu Tang (BHT), Si Ni Tang (SNT), and Xue Bi Tang (XBT) are ancient traditional Chinese formulas derived from Chinese herbs that are used to trea...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
This study aims to isolate marine invertebrates associated bacteria with antimicrobial activity from the Red Sea and tests their biosynthetic potential through the detection of PKS and NRPS gene clusters involved with the production of bioactive secondary metabolites. In this respect, fifty bacterial strains were isolated from eight different Red Sea marine invertebrates and screened for their antimicrobial activity against standard pathogenic bacteria (Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Bacillus subtilis ATCC 6633) and yeast (Candida albicans ATCC 10231) using the standard well diffusion assay....
Source: Biotechnology Reports - Category: Biotechnology Source Type: research
Publication date: Available online 20 July 2018Source: Protein Expression and PurificationAuthor(s): Sarah C. Bernier, Line Cantin, Christian SalesseAbstractPurification of recombinant proteins is often achieved using a purification tag which can be located either at the N- or C-terminus of a passenger protein of interest. Many purification tags exist and their advantages and limitations are well documented. However, designing fusion proteins can be a challenging task to get a fully expressed, soluble and highly purified passenger protein. Besides, there is a lack of systematic studies on the use of a single tag versus com...
Source: Protein Expression and Purification - Category: Biochemistry Source Type: research
Publication date: Available online 20 July 2018Source: Colloids and Surfaces B: BiointerfacesAuthor(s): I. Milošević, S. Rtimi, A. Jayaprakash, B. van Driel, B. Greenwood, A. Aimable, M. Senna, P. BowenAbstractFluorinated-titanium dioxide (TiO2-F) nanoparticles in a pure anatase polymorph was precipitated from solution by hydrolysis of titanium oxychloride, using urea and ammonia as precipitation agents and potassium fluoride as a source of fluorine anion. A further wet attrition milling in presence of glycine completed by a heat treatment allowed an additional nitrogen doping of TiO2 (TiO2-F&N-HT). The morphology ...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: September 2018Source: European Polymer Journal, Volume 106Author(s): Xinyu Zhou, Xiaokai Su, Zhengzhong Tan, Chuncai ZhouAbstractAntibacterial peptides as a novel antimicrobial agent have overwhelmingly caught researchers’ attention with unique superiority. Here, we report a series of triblock copolypeptides K10-b-Fn-b-K10 synthesized by sequential NCA ring-opening polymerization. The obtained triblock copolypeptides have good antibacterial efficacy against both S. aureus and E. coli. The hemolysis test has been conducted and it suggests that the triblock copolypeptides have low cytotoxicity and goo...
Source: European Polymer Journal - Category: Chemistry Source Type: research
In this study, two prenylflavonoids sanggenon C (SGC) and kuwanon G (KWG) exhibited strong inhibition on p-nitrophenyl-β-D-glucuronide-hydrolyzing activity in pooled human gut microbiota and eight bacterial isolates, while amoxapine, a previously reported Escherichia coli β-glucuronidase (EcoGUS) inhibitor, only showed poor inhibition on the pooled samples and relatively selective inhibition on individual strains with incomplete inhibition on Staphylococcus.pasteuri 3I10. Both prenylflavonoids exhibited mixed-type inhibition against the recombinant enzymes EcoGUS and S. pasteuri 3I10 β-glucuronidase (SpasGUS...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
ConclusionsRecurrent vaginitis should be taken into account as a possible adverse effect causing discomfort during long-term natalizumab treatment. Simple measures, such as probiotic administration and meticulous local hygiene, can provide adequate relief for such patients.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: August 2018Source: Journal of the Formosan Medical Association, Volume 117, Issue 8Author(s): Wan-Ju Yu, Shih-Yen Chen, Chi-Neu Tsai, Hsun-Ching Chao, Man-Shan Kong, Yi-Jung Chang, Cheng-Hsun ChiuBackground/PurposeRotavirus vaccines were launched in Taiwan since early 2006. Our study was aimed to figure out long-term extended molecular epidemiology in acute gastroenteritis (AGE) in hospitalized young children after rotavirus vaccination in Taiwan.MethodsDuring the 10-year period from January 2007 to December 2016, fecal samples from children under 5 years old with AGE hospitalized in Chang Gung Children's...
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
Karen Odens' little girl Sophia contracted the bacteria on February 5, 2014, from a mystery source in Detroit Lakes, Minnesota. Karen caught it too but survived four years. She died last week.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
In this study, a poly l-lactic acid (PLLA) fibrous mat was prepared by electrospinning, followed by surface modification with polydopamine (PDA), based on its strong adhesion performance and self-polymerization of dopamine. The PDA coating on the fibrous mat surface provided a reaction platform for heparin via a Michael-type addition reaction and a reductive surface for Ag+ in situ formation of silver nanoparticles (AgNPs) in AgNO3 solution. The structure and chemical composition of the fibrous mats were determined by scanning electronic microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and attenuated total reflect...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
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