Effect of knee flexion position and combined application of tranexamic acid on blood loss following primary total knee arthroplasty: a prospective randomized controlled trial

ConclusionsKeeping the knee in flexion position combined with topical and intravenous TXA application in patients undergoing primary unilateral TKA significantly reduced post-operative bleeding and the transfusion rate compared with what was found after treatment with extension knee position or single intravenous TXA application.Level of evidenceTherapeutic Level I

Source: International Orthopaedics - February 2, 2018 Category: Orthopaedics Source Type: research