Single-Antigen-Mismatched Unrelated Hematopoietic Stem Cell Transplantation Using High-Dose Post-Transplantation Cyclophosphamide is a Suitable Alternative for Patients Lacking HLA-Matched Donors
• Single-antigen MMUD transplants using PTCy has similar survival outcomes that MUD transplants.• PTCyMMUD seems to be associated to low rates of moderate/severe chronic GVHD.• This platform may expand the donor pool for patients who lack a matched related or unrelated donor.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Ana Sofia Jorge, Mar ía Suárez-Lledó, Arturo Pereira, Gonzalo Gutierrez, Francesc Fernández-Avilés, Laura Rosiñol, Noemí Llobet, Teresa Solano, Álvaro Urbano-Ispízua, Montserrat Rovira, Carmen Martínez Source Type: research