Donor Cell-Derived Hematological Neoplasms after Hematopoietic Stem Cell Transplantation. a Systematic Review.

• Leukemic transformation of donor hematopoietic stem cells provides a useful model to study the mechanisms involved in leukemogenesis.• A systematic analysis of 137 cases reported in the literature highlights several factors that may contribute to the development of donor cell derived hematolog ical neoplasms after allo-SCT.

Source: Biology of Blood and Marrow Transplantation - February 2, 2018 Category: Hematology Authors: Julia Su árez-González, Carolina Martínez-Laperche, Mi Kwon, Pascual Balsalobre, Diego Carbonell, María Chicano, Gabriela Rodríguez-Macías, David Serrano, Jorge Gayoso, José Luis Díez-Martín, Ismael Buño Source Type: research