Higher Donor Apheresis Blood Volumes are Associated with a Reduction in Relapse Risk and Improved Survival in Reduced Intensity Allogeneic Transplants with Unrelated Donors

• Donor apheresis volume ≥ 15L is associated with better survival after transplant.• The survival advantage is driven by a decrease in relapse risk.• Higher apheresis volumes are associated with higher T-cell but not CD34+ doses.

Source: Biology of Blood and Marrow Transplantation - February 2, 2018 Category: Hematology Authors: Lisa M. Crisalli, Joanne T. Hinkle, Christopher C. Walling, Mary Sell, Noelle V. Frey, Elizabeth O. Hexner, Alison W. Loren, Selina M. Luger, Edward A. Stadtmauer, David L. Porter, Ran Reshef Source Type: research