Chlamydia trachomatis inhibits the production of pro-inflammatory cytokines in human PBMCs through induction of IL-10.

CONCLUSION: IL-10 is up-regulated in an ERK- and p38-dependent fashion in stimulated human PBMCs. IL-10 inhibits the production of pro-inflammatory cytokines by activating the JAK/STAT signalling pathway.
PMID: 29388547 [PubMed - in process]

Source: Journal of Medical Microbiology - February 1, 2018 Category: Microbiology Authors: Du K, Zhou M, Li Q, Liu XZ Tags: J Med Microbiol Source Type: research