Estimated Biopsy Rate Varies After Breast Cancer Treatment

Incidence of breast biopsy higher among women treated with brachytherapy versus whole - breast irradiation
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Gynecology, Oncology, Pathology, Radiology, Surgery, Journal, Source Type: news

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Conclusions: Hypofractionated 2-day APBI using brachytherapy resulted in excellent clinical outcomes with acceptable chronic toxicities.
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Breast Source Type: research
Studies have shown that an additional mean dose of 1  Gy to the heart can increase the relative risk of cardiac events. The purpose of this study was to quantify the dose delivered to the heart and left anterior descending artery (LAD) in a series of patients with left-sided breast cancer (BC) or ductal carcinoma in situ treated with multicatheter-ac celerated partial breast irradiation (MC-APBI) at a single institution.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research
To assess the feasibility of high-dose-rate perioperative multicatheter interstitial brachytherapy to deliver accelerated partial breast irradiation (APBI) in selected patients with early breast cancer.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research
This study aimed to estimate the probability of an unfavourable aesthetic outcome (AO) 2  years after breast-conserving therapy (BCT) and evaluate the possible influence of brachytherapy (BT) and external beam radiotherapy (EBRT) boost on patient-reported outcomes (PROs) and AO.Patients and methodsPatients treated with BCT starting April 2015 were prospectively included. Selection of the boost technique followed an in-house flowchart based on the depth of the tumour bed. An electron boost was performed for a  superficial clinical target volume (maximum 28 mm under the epidermis), a BT boost was proposed in...
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
ConclusionsBrachytherapy APBI is associated with higher rates of grade 1 fibrosis and seroma than 3D-CRT but lower rates of grade 1 edema and grade 2-3 pain than 3D-CRT. Rates of radiation oncologist-reported “fair” or “poor” cosmetic outcome are higher with brachytherapy. We identified dosimetric parameters that predict reduced risk of adverse cosmetic outcome after brachytherapy-based APBI. Ipsilateral breast recurrence was equivalent for brachytherapy and 3D-CRT.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
ConclusionsBBC represents a complex challenge for doctors, because in some cases there is a tendency to use more aggressive treatments and, at the same time, it is not easy to achieve the timing for the correct treatment.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Publication date: September–October 2018Source: Reports of Practical Oncology &Radiotherapy, Volume 23, Issue 5Author(s): Sara Imboden, Laura Knabben, Michael D. Mueller, Andreas R. Günthert, Kristina LösslAbstractAn 81-year-old patient developed an exulcerous tumor in her left breast 21 years after breast cancer treatment with lumpectomy and adjuvant radiotherapy. At the time of the initial treatment 21 years ago, whole breast irradiation was performed with a prescribed dose of 48 Gy and a maximal dose of 69 Gy. In addition, the patient received a 14.7 Gy boost with multicatheter brachytherapy as...
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
This report reviews our available data to provide an analysis of patient outcomes over 12 years of use at a single institution. A retrospective review was conducted of records of 150 patients who underwent APBI or attempted APBI after breast-sparing surgeries between 2006 and 2017. These charts were analyzed for documentation of patient age, cancer stage, incidence of recurrence, and posttreatment complications. Of the patients evaluated, 99 per cent (149/150) completed treatment. The median time since treatment completion is now 8.9 years. One hundred eleven patients (74% ) are now greater than five years posttreatment. I...
Source: The American Surgeon - Category: Surgery Authors: Tags: Am Surg Source Type: research
The INTRABEAM radiotherapy system is the most commonly used electronic brachytherapy (eBT) system in Europe for cancer treatment. To deliver the prescribed dose, medical physicists use the dose distribution data provided by the manufacturer (Zeiss). This work aims at verifying the correctness of these data for the specific case of breast cancer treatment by comparing the relative dose distribution predicted by Zeiss with that measured using gel dosimetry and that calculated using Monte Carlo simulation.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Source Type: research
Authors: Yoshida K, Otani Y, Nose T, Yoden E, Asahi S, Tsukiyama I, Dokiya T, Saeki T, Fukuda I, Sekine H, Kumazaki Y, Takahashi T, Kotsuma T, Masuda N, Nakashima K, Matsumura T, Nakagawa S, Tachiiri S, Moriguchi Y, Itami J, Oguchi M Abstract We initiated the first multi-institutional prospective study of accelerated partial breast irradiation for early breast cancer in Japan. Our early clinical results showed that the treatment methods were technically reproducible between institutions and showed excellent disease control at a median follow-up of 26 months in our previous report. At present, total 46 patients from...
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
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