Estimated Biopsy Rate Varies After Breast Cancer Treatment
Incidence of breast biopsy higher among women treated with brachytherapy versus whole - breast irradiation
ConclusionsBBC represents a complex challenge for doctors, because in some cases there is a tendency to use more aggressive treatments and, at the same time, it is not easy to achieve the timing for the correct treatment.
Publication date: September–October 2018Source: Reports of Practical Oncology &Radiotherapy, Volume 23, Issue 5Author(s): Sara Imboden, Laura Knabben, Michael D. Mueller, Andreas R. Günthert, Kristina LösslAbstractAn 81-year-old patient developed an exulcerous tumor in her left breast 21 years after breast cancer treatment with lumpectomy and adjuvant radiotherapy. At the time of the initial treatment 21 years ago, whole breast irradiation was performed with a prescribed dose of 48 Gy and a maximal dose of 69 Gy. In addition, the patient received a 14.7 Gy boost with multicatheter brachytherapy as...
Authors: Yoshida K, Otani Y, Nose T, Yoden E, Asahi S, Tsukiyama I, Dokiya T, Saeki T, Fukuda I, Sekine H, Kumazaki Y, Takahashi T, Kotsuma T, Masuda N, Nakashima K, Matsumura T, Nakagawa S, Tachiiri S, Moriguchi Y, Itami J, Oguchi M Abstract We initiated the first multi-institutional prospective study of accelerated partial breast irradiation for early breast cancer in Japan. Our early clinical results showed that the treatment methods were technically reproducible between institutions and showed excellent disease control at a median follow-up of 26 months in our previous report. At present, total 46 patients from...
Conclusions: The deviations between planned and measured dose values were markedly influenced by the proximity of the detector to the PTV because where the edema exerts, the greatest influence on the tube applicator geometry. The positioning of the patient during irradiation must correspond to the positioning in the planning CT. Further studies are needed to investigate the role of in vivo dosimetry during interstitial brachytherapy as a routine procedure. PMID: 30038643 [PubMed]
In this study the maximum dose numbers are used after evaluating 30 left breast patients.
Accelerated partial breast irradiation (APBI) is a treatment option for selected early stage breast cancer patients. Some APBI techniques lead to skin toxicity with the skin dose as main risk factor. Spacers are effective and safe in prostate brachytherapy to protect the rectum. We hypothesize that a spacer injection between the dermis and the target volume may reduce the skin dose in breast brachytherapy.
Patients that have a local resection of early stage breast cancer are frequently treated with high dose rate brachytherapy utilizing APBI. The bulk of the current data for APBI treatments are based solely on large academic centers. Therefore this study looks retrospectively at the local, regional, and distant control of all patients in a community hospital setting upon completion of the APBI treatment.
Permanent breast seed implant (PBSI) is an accelerated partial breast irradiation modality for the treatment of early-stage breast cancer. Stranded 103Pd seeds are permanently implanted in and around the post-lumpectomy seroma according to a pre-treatment CT-based plan. Questions have arisen regarding the potential post-implant migration of seeds given the mobility of breast tissue. Further, seed displacements and coalescence have been observed in the weeks following implant by centres performing the technique.
A series of clinical trials and prospective studies investigating intraoperative radiation therapy as a safe modality following breast conserving surgery has led to single institution studies of electronic brachytherapy for low risk breast cancer patients. Despite minimal data on the clinical effectiveness of electronic brachytherapy as a safe modality or alternative to whole breast radiation following breast conserving surgery, the adoption of this technology appears to account for the rise in intraoperative radiation therapy in the 21st century.
Prior studies have shown an increased use of accelerated partial breast irradiation (APBI), particularly brachytherapy, in the United States during the 21st century. However, more recent studies examining these trends are lacking. Therefore, we examined national trends and predictors of APBI use for patients with breast cancer.