MALDI imaging detects endogenous digoxin in glioblastoma cells infected by Zika virus —Would it be the oncolytic key?

This study brings light to unexpectedly induced metabolic changes, as endogenous digoxin as important biomarker for ZIKV‐GBM group, associated with cytopathic effects induced by viral infection. These result evidences that genetically engineered ZIKV might be a potential new strategy for neural cancer management through the induction of endogenous digoxin synthesis in GBM cells.

Source: Journal of Mass Spectrometry - February 2, 2018 Category: Chemistry Authors: Estela de O. Lima, Tatiane M. Guerreiro, Carlos Fernando O.R. Melo, Diogo N. Oliveira, Daisy Machado, Marcelo Lancelloti, Rodrigo R. Catharino Tags: ACCELERATED COMMUNICATION Source Type: research