Epidermal Growth Factor Attenuated the Expression of Inflammatory Cytokines in Human Epidermal Keratinocyte Exposed to Propionibacterium acnes.

Conclusion: These results suggest that EGF attenuated P. acnes-induced inflammatory responses, at least in part, through the modulation of TLR2 signalling, and the topical application of rhEGF may be beneficial to relieve the inflammatory reactions of acne.
PMID: 29386833 [PubMed]

Source: Annals of Dermatology - February 2, 2018 Category: Dermatology Tags: Ann Dermatol Source Type: research