Prostate cancer now kills more people than breast cancer, UK figures reveal

Male illness now third most common cause of cancer death behind lung and bowelProstate cancer has become the third most common cause of cancer death in the UK, overtaking breast cancer, despite improvements in survival rates for both.The top cancer killer in the UK is lung cancer, which claimed 35,486 lives in 2015, followed by colorectal cancer, with a toll of 16,067 people.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Prostate cancer Cancer research Science UK news Health Medical research Society Source Type: news

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Authors: Alexander W Abstract We review key findings in the areas of prostate cancer, non-small-cell lung cancer, breast cancer, esophageal cancer, pancreatic cancer, leukemias, metastatic colon cancer, and one session on molecular profiling guidance of therapy. PMID: 30100691 [PubMed]
Source: P and T - Category: Drugs & Pharmacology Tags: P T Source Type: research
Publication date: Available online 7 July 2018Source: SteroidsAuthor(s): Nguyen Hoai Nam, Ninh Thi Ngoc, Tran Thi Hong Hanh, Nguyen Xuan Cuong, Nguyen Van Thanh, Do Thi Thao, Do Cong Thung, Phan Van Kiem, Chau Van MinhAbstractUsing various chromatographic separations, seventeen steroids including seven new compounds, verrucorosteroids A−F (1−6) and verrucorosterone (7), were isolated from the Vietnamese gorgonian Verrucella corona. Their structures were elucidated by spectroscopic analysis, including HR QTOF MS, 1D and 2D NMR. Among isolates, verrucorosterone (7), 5,6α-epoxy-3β-hydroxy-(22E)-ergosta-...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 10 July 2018Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): Niamh Mc Namee, Lorraine O'DriscollAbstractExtracellular vesicles (EVs) including exosomes, microvesicles, oncosomes, and microparticles have been associated with communicating anti-cancer drug-resistance. The in vitro, pre-clinical in vivo and patients' data linking EVs to drug-resistance (and the specific drugs involved) in breast cancer, prostate cancer, lung cancer, ovarian cancer, haematological malignancies, colorectal cancer, gastric cancer, pancreatic cancer, glioblastoma, neuroblastoma, melanoma...
Source: Biochimica et Biophysica Acta (BBA) Reviews on Cancer - Category: Cancer & Oncology Source Type: research
Publication date: Available online 7 July 2018Source: SteroidsAuthor(s): Nguyen Hoai Nam, Ninh Thi Ngoc, Tran Thi Hong Hanh, Nguyen Xuan Cuong, Nguyen Van Thanh, Do Thi Thao, Do Cong Thung, Phan Van Kiem, Chau Van MinhAbstractUsing various chromatographic separations, seventeen steroids including seven new compounds, verrucorosteroids A−F (1−6) and verrucorosterone (7), were isolated from the Vietnamese gorgonian Verrucella corona. Their structures were elucidated by spectroscopic analysis, including HR QTOF MS, 1D and 2D NMR. Among isolates, verrucorosterone (7), 5,6α-epoxy-3β-hydroxy-(22E)-ergosta-...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONS: Palliative care use in solid cancer tumors is variable, with a preference for patients with lung cancer, younger age, known insurance status, and higher educational level. PMID: 29807486 [PubMed - as supplied by publisher]
Source: Journal of Palliative Care - Category: Palliative Care Tags: J Palliat Care Source Type: research
Conclusions: PET imaging with radiolabeled amino acids has been shown be effective for brain tumor imaging, providing high contrast between tumor and normal brain parenchyma. The synthetic leucine amino acid analogue, fluciclovine has been recently FDA approved for evaluation of biochemical recurrent prostate cancer. Recent studies have been published demonstrating the utility of fluciclovine for glioma evaluation. Our findings suggest that fluciclovine can similarly be used for evaluation of new or recurrent brain metastasis in patients who previously have undergone brain radiotherapy where MRI is often limited due to bac...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Preclinical Probes for Oncology Posters Source Type: research
Authors: Wang Y, Lan GB, Peng FH, Xie XB Abstract Renal transplantation is associated with an increased risk of cancers at multiple sites; however, the relationships between increased cancer risk and participant characteristics remain unclear. We searched PubMed, Embase, and the Cochrane Library to identify prospective observational studies performed up to July 2017. Totally 11 prospective studies reported data on 79,988 renal transplant recipients were included. Renal transplant recipients were found to display a higher risk of all cancers (standard incidence ratio [SIR]: 2.89; 95% CI: 2.13-3.91; P
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
In battle, the standard-bearer honorarily carries the flag, which represents the nobility and purpose of continuing the fight. In the war on cancer many advances have been made that surround the more common cancers such as breast cancer, prostate cancer, colon cancer, and lung cancer. However, there are these rare tumors of mesenchymal origin, sarcomas, which have disproportionately advanced the front lines of our understanding of cancer mechanisms. It is because of sarcoma research that we even know what oncogenes and tumor suppressor genes are.
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research
In battle, the standard-bearer honorarily carries the flag, which represents the nobility and purpose of continuing the fight. In the war on cancer many advances have been made that surround the more common cancers such as breast cancer, prostate cancer, colon cancer, and lung cancer. However, there are these rare tumors of mesenchymal origin, sarcomas, which have disproportionately advanced the front lines of our understanding of cancer mechanisms. It is because of sarcoma research that we even know what oncogenes and tumor suppressor genes are.
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research
Authors: Peng X, Shi J, Sun W, Ruan X, Guo Y, Zhao L, Wang J, Li B Abstract IL-6 is critical for tumorigenesis. However, previous studies on the association of IL-6 promoter polymorphisms with predisposition to different cancer types are somewhat contradictory. Therefore, we performed this meta-analysis regarding the relationship between IL-6 promoter single nucleotide polymorphisms and cancer susceptibility and prognosis. Up to April 2017, 97 original publications were identified covering three IL-6 promoter SNPs. Our results showed statistically significant association between IL-6 promoter and cancer risk and pr...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
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