IGF-1R Inhibitor Ameliorates Diabetic Nephropathy with Suppressed HMGN1/TLR4 Pathway.

CONCLUSION: IGF-1R inhibitor might have therapeutic potential in DN through inhibition of HMGN1/TLR4 pathway.
PMID: 29384065 [PubMed - as supplied by publisher]

Source: Endocrine, Metabolic and Immune Disorders Drug Targets - January 30, 2018 Category: Endocrinology Authors: Jiali Y, Jingjing D, Rong D, Yi S, Yingjie N, Fuxun Y, Lima Z, Yan Z Tags: Endocr Metab Immune Disord Drug Targets Source Type: research