Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model

ConclusionIt does not appear that intermittent bolus administration of intravenous benzodiazepines for alcohol withdrawal influenced renal function or anion gap regardless of number of administered doses, amount of PG received, or the estimated PG concentration.

http://link.springer.com/10.1007/s13318-018-0462-1

Source: European Journal of Drug Metabolism and Pharmacokinetics - February 1, 2018 Category: Drugs & Pharmacology Source Type: research