Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer

Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancerTargeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer, Published online: 02 February 2018; doi:10.1038/s41388-017-0108-9Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer

Source: Oncogene - February 2, 2018 Category: Cancer & Oncology Authors: Özge Saatci Simone Borgoni Özge Akbulut Selvi Durmu ş Umar Raza Erol Ey üpoğlu Can Alkan Aytekin Akyol Özgür Kütük Stefan Wiemann Özgür Şahin Source Type: research