Pro Football Players May Die Earlier Than Their Peers, Study Says

The professional football industry has been rocked by plenty of bad press in recent years, from domestic violence charges to studies linking the sport to chronic brain injury. Now, just ahead of this weekend’s Super Bowl, a new study casts another shadow over the game: Career players in the National Football League (NFL) have slightly higher rates of early death than their peers who didn’t play professionally, according to a report published in JAMA. The difference in mortality rate between NFL players and non-NFL players was not statistically significant, meaning that the total number of deaths in the study was too low to rule out that the results could be due to chance. But the study authors say the findings are still concerning, and that scientists should continue tracking football players after retirement to see if stronger links can be found. The new study stands in contrast to previous research suggesting that football players live longer than members of the general public. On one hand, those previous findings make sense, says Dr. Atheendar Venkataramani, lead author of the new study and assistant professor of medical ethics and health policy at the University of Pennsylvania’s Perelman School of Medicine. Professional athletes spend their careers in top physical shape and get plenty of exercise, and even after retirement, they often have the money and resources to stay fit. They also get the best health care. But playing football has also been linke...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized chronic traumatic encephalopathy concussions cte football players football cte study football injuries football safety healthytime is football dangerous is football safe onetime Research why is football dangerous Source Type: news

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Authors: Ohnari K, Okada K, Higuchi O, Matsuo H, Adachi H Abstract An 82-year-old woman developed neck weakness and dysarthria with antibodies against acetylcholine receptor (AChR) and low-density lipoprotein receptor-related protein 4 (LRP4). Myasthenia gravis (MG) was diagnosed by edrophonium and repetitive nerve stimulation tests. Her symptoms resolved completely by immunotherapy. One year later, she presented with muscle weakness and bulbar palsy accompanied by atrophy and fasciculation. Her tendon reflexes were brisk, and Babinski's sign was positive. She was diagnosed with probable amyotrophic lateral scleros...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Publication date: Available online 16 October 2018Source: Journal of Neuroscience MethodsAuthor(s): Wilson BarnabasAbstractBrain specific drug delivery is one of the most interesting and challenging areas of research. The blood-brain barrier separates the brain from blood and acts as a barrier to protect the brain from microorganisms, neurotoxins and chemical substances. But, the same mechanism poses an obstacle for the entry of many drugs into the brain. Worldwide, approximately 1.5 billion people are suffering from CNS disorders, such as Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, amyotrophi...
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder leading to chronic respiratory failure. Few studies have investigated ALS-related dyspnoea, and none have characterised the emotional distress it inflicts. We hypothesised that ALS-related dyspnoea has a strong affective component that relates to quality of life.
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European Journal of Neurology,Volume 0, Issue ja, -Not available-.
Source: European Journal of Neurology - Category: Neurology Authors: Source Type: research
TAR DNA binding protein 43 (TDP-43) is the main disease protein in most patients with amyotrophic lateral sclerosis (ALS) and about 50% of patients with frontotemporal dementia (FTD). TDP-43 pathology is not r...
Source: Molecular Neurodegeneration - Category: Neurology Authors: Tags: Research article Source Type: research
This study systematically evaluated the relationship between BMI and survival in patients with ALS. Methods The PubMed database was searched to identify all available studies reporting time-to-event data. Eight studies with 6,098 patients fulfilled the eligibility criteria. BMI was considered a continuous and ordered variable. Interstudy heterogeneity was assessed by the Cochran Q test and quantified by the I2 metric. Fixed- or random-effects odds ratios summarized pooled effects after taking interstudy variability into account. Significance was set at p
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Muscle&Nerve, EarlyView.
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Publication date: Available online 12 October 2018Source: Neuroscience LettersAuthor(s): Yan-Ming Wei, Bo HanAbstractMany neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), are characterised by the intracellular appearance of protein aggregates or insoluble materials. Accelerated removal of related toxic proteins might be beneficial for these diseases. Here we describe an inducible role of Beclin1, an essential regulator for autophagy, in degradation of the familial ALS-linked Cu/Zn superoxide dismutase 1 (SOD1) mutant. We confirmed that the SOD1 mutant exhibited an increased RIPA (radioimmune precipi...
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