Lancet: Cancer survival rates improve but vary widely
While cancer survival rates are generally increasing worldwide, there are still...Read more on AuntMinnie.comRelated Reading: Cancer deaths continue to fall, but CT lung screening lags Colorectal cancer mortality starts edging back up CDC: Cancer screening lags goals ACS: U.S. cancer death rates continue to fall JAMA: Cancer deaths fall 20% in U.S. since 1980
Publication date: Available online 21 February 2018 Source:The Journal of Molecular Diagnostics Author(s): Yang Wang, Cindy L. Vnencak-Jones, Justin M. Cates, Chanjuan Shi Elevated microsatellite alterations at selected tetranucleotide repeats are common in colorectal cancers (CRCs). Its association with classic mono/dinucleotide microsatellite instability (MSI) is unknown. We assessed the stability of 13 tetranucleotide and three pentanucleotide repeat markers on both tumor and normal tissue from a cohort of 22 MSI-high (MSI-H) and 107 microsatellite stable (MSS) CRCs. When present, instability was observed at tetra/pent...
ConclusionMeat ingestion led to the excretion of several nitrogen‐containing compounds, but although a metabolic signature was detected for meat ingestion, the impact of cooking process was not detectable at the level of urinary metabolic signature in our experimental conditions.This article is protected by copyright. All rights reserved
Publication date: Available online 22 February 2018 Source:Pathology - Research and Practice Author(s): Nam Jin Yoo, Min Sung Kim, Ju Hwa Lee, Chang Hyeok An, Sug Hyung Lee
We present our series of 21 cases that support this safe, reliable, and simple method for intact uterine delivery during robotic hysterectomy in minimally invasive gynecological oncology practice.
Conclusion: Trained SVM classifier based on arm-level CNVs can be used as a promising method to screen early-stage CRC.Cell Physiol Biochem 2018;45:1444 –1454
Conclusion: After a decade since the introduction of bevacizumab, no effective predictive biomarkers are available in routine clinical practice. In this review, we summarized the potential candidate dynamic biomarkers that may play a role in this setting.
This study shows that andrographolide inhibits the development of osteoclasts ( = the cells that chew away at our bones, which is fine in a healthy situation, not fine in cancer where everything goes nutso), while increasing the presence of osteoblasts (bone builders). The researchers say that the current therapies used to treat osteolytic diseases have many unwanted side effects. And they’re not just referring to bisphosphonates (which can cause osteonecrosis of the jaw) but also to new treatments such as the monoclonal antibody denosumab, Denosumab can cause low calcium levels, weakness, constipation, bac...
ConclusionExercise training is feasible in patients with colorectal cancer after completion of adjuvant chemotherapy. The main problem encountered during the study was compliance. To improve compliance of exercise training, several measures were adapted for the upcoming prospective randomized ABCSG C08 Exercise II study.
ConclusionsThis study generated qualitative data on survivorship impacts and components of survivor resilience in NZ. It also provided insights into the need for better strategies and pathways to help the NZ health system be more responsive to both M āori and non-Māori survivors.Implications for cancer survivorsSurvivor impacts create vulnerabilities that are experienced and described differently by individuals and groups in NZ. Tailored survivor support that can enhance resilience and support relationships is needed in NZ.
Authors: Jia B, Xia L, Cao F Abstract Colorectal cancer (CRC) develops from the colon or rectum and is the fourth highest inducer of cancer mortality. In the present study, cancer tissues and normal tissues were extracted from patients with CRC who were treated in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine (Jinan, China). Reverse transcription-quantitative polymerase chain reaction demonstrated that the expression level of miR-766-5p was significantly higher (P