Biopsy rate is low after breast cancer

The rate of follow-up biopsies after breast cancer is relatively low -- a fact...Read more on AuntMinnie.comRelated Reading: 3D-printed breast biopsy device boosts accuracy Women overestimate breast cancer risk, prefer biopsy FDA clears GE MBI biopsy accessory AI could help reduce unnecessary breast biopsies FDA clears Hologic's Affirm prone biopsy system
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

Related Links:

Contributors : Borbala Szekely ; Xiaotong LiSeries Type : Expression profiling by arrayOrganism : Homo sapiensLittle is known about how the immune microenvironment of breast cancer evolves during disease progression. The goal of this project was to examine immune gene mRNA expression in primary tumors (P) and metastatic lesions (M). The expression of 730 immune-related genes was measured using the Nanostring PanCancer Immune Gene Panel.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
Publication date: Available online 19 August 2018Source: Sensors and Actuators B: ChemicalAuthor(s): Kruthika Kikkeri, Sepeedah Soltanian-Zadeh, Ayesha N. Shajahan-Haq, Lu Jin, Jeannine Strobl, Robert Clarke, Masoud AgahAbstractThe majority of breast tumors express estrogen receptors (ER), and are treated with endocrine therapy (ET) drugs to target ERs and estrogen (E2) biosynthesis in the management of early and metastatic ER + breast cancer. However, ~50% of patients receiving an ET exhibit either intrinsic (de novo) resistance or acquire resistance to these treatments despite persistent expression of ER in...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
AbstractPurpose of ReviewTriple-negative breast cancer (TNBC) accounts for 15 –20% of diagnosed breast tumours, with higher incidence in young and African-American women, and it is frequently associated with BRCA germline mutations. Chemotherapy is the only well-established therapeutic option in both early- and advanced-stages of the disease. TNBC tumours relapse earlier af ter standard anthracycline- and/or taxane-based chemotherapy treatments, generally within 1–3 years after the diagnosis, and often develop visceral metastases, representing the subtype with a worse prognosis among all breast cancers. In...
Source: Current Oncology Reports - Category: Cancer & Oncology Source Type: research
Conclusion This study provides a detailed, large-scale picture of the relationship between the shape of the alcohol market in local areas and the levels of alcohol-related hospital admissions in those areas.  It suggests that there is a relationship, and that it is marked especially where there is a high density of any on-trade outlets or licensed convenience stores.  It suggests that this relationship is largely the same for men and women, and applies is a similar fashion irrespective of the relative affluence of a given area. It also suggests that while alcohol outlet density is already high across England, inc...
Source: Alcohol Research UK - Category: Addiction Authors: Tags: Alcohol Insights Source Type: news
Authors: Liu H, Tang L, Li X, Li H Abstract Triptolide has been demonstrated to induce tumor cell apoptosis. However, the role of triptolide in breast cancer angiogenesis remains unclear. The present study aimed to investigate the function of triptolide in breast cancer and the molecular mechanisms underlying this. The results revealed that triptolide could significantly decrease the expression of vascular endothelial growth factor A (VEGFA) in Hs578T and MDAMB231 breast cancer cells. Furthermore, human umbilical vein endothelial cells were used to perform tube formation and bromodeoxyuridine incorporation assays, ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Leptin promotes the growth of breast cancer by upregulating the Wnt/β-catenin pathway. Exp Ther Med. 2018 Aug;16(2):767-771 Authors: Liang X, Wang S, Wang X, Zhang L, Zhao H, Zhang L Abstract The present study aimed to investigate the role of leptin in the growth of breast cancer. In the present study, expression of leptin in tumor tissues and adjacent tissues was detected by reverse transcription-quantitative polymerase chain reaction. Serum leptin in patients with breast cancer and normal healthy controls was detected by ELISA. Different concentrations of leptin were used to treat breast cancer ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
In conclusion, curcumin inhibited the proliferation of breast cancer cells and induced G2/M phase cell cycle arrest and apoptosis, which may be associated with the decrease of CDC25 and CDC2 and increase of P21 protein levels, as well as inhibition of the phosphorylation of Akt/mTOR and induction of the mitochondrial apoptotic pathway. The findings of the present study may provide a basis for the further study of curcumin in the treatment of breast cancer. PMID: 30116377 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Wang F, Zhu Y, Fang S, Li S, Liu S Abstract Ovarian cancer is the leading cause of mortality resulting from gynecologic cancer. A common anti-ovarian tumor drug is cisplatin; however, repeated use of cisplatin causes severe resistance and leads to poor long-term survival rate in ovarian cancer patients. Recently, it was reported that lanthanum chloride (LaCl3) may inhibit tumor growth and induce apoptosis in certain cancer cells. In the present study, the effect of LaCl3 on ovarian cancer was determined in vivo and in vitro. A cisplatin-sensitive human ovarian cancer cell line, COC1, was used in the curren...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Yu S, Zhang Y, Chen L, Li Q, Du J, Gao Y, Zhang L, Yang Y Abstract To improve the bio-solubility and sustained-release properties of a carbon nanotube (CNT)-drug complex, the present study used a hydrophilic polymer, polyethylene glycol (PEG), and β-estradiol (E2), which targets the estrogen receptor in human breast cancer cells (HBCCs), to modify CNTs carrying lobaplatin (LBP) to form E2-PEG-CNT-LBP. The in vitro inhibitory effects against HBCCs and the in vivo pharmacological effect of the complex on heart, liver and kidney tissues were also evaluated. The results indicated that the inhibitory effec...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Publication date: Available online 18 August 2018Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Karolina Chrabaszcz, Agnieszka Jasztal, Marta Smęda, Bartosz Zieliński, Aneta Blat, Max Diem, Stefan Chlopicki, Kamilla Malek, Katarzyna M. MarzecAbstractAn application of FTIR spectroscopic imaging for the identification and visualization of early micrometastasis from breast cancer to lungs in a murine model is shown. Spectroscopic and histological examination is focused on lung cross-sections derived from animals at the early phase of metastasis (early micrometastasis, EM) as compared to h...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
More News: Breast Cancer | Cancer | Cancer & Oncology | Radiology | Women