Histoid leprosy: clinical and histopathological analysis of patients in follow ‐up in University Clinical Hospital of endemic country

ConclusionThe prevalence of HL was similar to previous reports. However, all histoid patients were “de novo” cases, differing from published studies. Fusocellular macrophage transformation could be explained by the differences in cytoskeleton proteins expressed in histoid lesions in comparison to other leprosy variants, with emphasis on vimentin and smooth muscle actin.
Source: International Journal of Dermatology - Category: Dermatology Authors: Tags: Tropical Medicine Rounds Source Type: research