A couple returned from vacation with itchy feet. Hookworms were tunneling through their skin.
It started with an itch after a stroll on a Caribbean beach, but in just a few days it had morphed into a gut-churning travel nightmare. In mid-January Eddie Zytner and Katie Stephens, a couple from Windsor, Ontario, went on a vacation to Punta Cana, a resort town on the eastern coast of the Dominican Republic. At some […]Related:Social egg freezing is a numbers game that many women don’t understandFDA wants to curb abuse of Imodium, ‘the poor man’s methadone’This flu season is on track to be the worst in nearly a decade
Publication date: Available online 30 March 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Stefanie H. Meeuwis, Henriët van Middendorp, Antoinette I.M. van Laarhoven, Cora van Leijenhorst, Gustavo Pacheco-Lopez, Adriana P.M. Lavrijsen, Dieuwke S. Veldhuijzen, Andrea W.M. Evers
(HAMBURG, Pa.) — The spring breezes of 2020 are carrying more than just tree pollen. There’s a whiff of paranoia in the air. For millions of seasonal allergy sufferers, the annual onset of watery eyes and scratchy throats is bumping up against the global spread of a new virus that produces its own constellation of respiratory symptoms. Forecasters are predicting a brutal spring allergy season for swaths of the U.S. at the same time that COVID-19 cases are rising dramatically. That’s causing angst for people who never have had to particularly worry about their hay fever, other than to stock up on antihista...
Conditions: Atopic Dermatitis; Pruritus; Pruritus Chronic; Dermatitis Interventions: Drug: Naltrexone; Other: Placebo Sponsor: University of Minnesota Not yet recruiting
Itch, initiated by the activation of sensory neurons, is frequently associated with dermatological diseases. MrgprA3+ sensory neurons have been identified as one of the major itch-sensing neuronal populations. Mounting evidence has demonstrated that peripheral pathological conditions induce physiological regulations of sensory neurons, which is critical for the maintenance of chronic itch sensation. However, the underlying molecular mechanisms are not clear. Here we performed RNA sequencing of genetically labeled MrgprA3+ neurons under both na ïve and allergic contact dermatitis conditions.
lsh S Abstract We were fascinated and heartened to read this very helpful commentary1 on the study by Redhu et al2 who describe some precise physico-biological pathways that link skin barrier disruption to itch in atopic dermatitis (AD). This may well explain how curtailing scratching in AD with the simple behavioural technique of habit reversal can so dramatically improve the condition3. It is important to note that scratching in AD over time often becomes not only a response to itch, but also to both habit and mental state. PMID: 32222068 [PubMed - as supplied by publisher]
Chronic nodular prurigo (CNPG) is a multifactorial skin disease characterized by itchy papules and nodules, usually resistant to standard treatment and associated to markedly impaired quality of life.
CORONAVIRUS cases are increasing daily and with new cases comes a new set of symptoms. A fit and healthy gym manager from Hull as revealed the symptoms she suffered in the hopes of raising awareness for others.
Anterior cingulate cortex (ACC) plays important roles in sensory perception including pain and itch. Neurons in the ACC receive various neuromodulatory inputs from subcortical structures, including locus coeru...
ConclusionsQualitative data from NLP, being more patient-centric than data from clinical standardized measures, provide a more comprehensive view of the burden of AD to inform disease management.
AbstractPurposeProgressive familial intrahepatic cholestasis (PFIC) is a hereditary disease characterized by cholestasis, which may cause jaundice, severe pruritus, and cirrhosis in the later stages. By the invention of biliary diversion methods, these patients were prevented from undergoing liver transplant. Using biliary diversion techniques, the entero-hepatic cycle was interrupted. This lowers the bile acid pool and resolves the pruritus. Herein, we report 44 cases of PFIC who underwent partial internal biliary diversion (PIBD) and long-term follow-up of these children. This comprises the largest case series of PIBD.Me...