A novel cell line generated using the CRISPR/Cas9 technology as universal quality control material for KRAS G12V mutation testing

ConclusionThe novel KRAS G12V cell line generated using the CRISPR/Cas9 gene editing system is suitable as a quality control material for all current detection methods and provides a new direction in the development of quality control material.

Source: Journal of Clinical Laboratory Analysis - January 1, 2018 Category: Laboratory Medicine Authors: Shiyu Jia, Rui Zhang, Guigao Lin, Rongxue Peng, Peng Gao, Yanxi Han, Yu Fu, Jiansheng Ding, Qisheng Wu, Kuo Zhang, Jiehong Xie, Jinming Li Tags: RESEARCH ARTICLE Source Type: research