Comprehensive up-to-date review of toxic alcohol poisoning

3.5 out of 5 stars Toxic Alcohols. Kraut JA, Mullins ME. N Engl J Med 2018 Jan 18;378:270-280. Reference This is a good general review and update of clinical issues regarding the major toxic alcohols: methanol, ethylene glycol, isopropanol, diethylene glycol, and propylene glycol. The article is chockablock with information, and would I think be somewhat difficult to follow if one was not already familiar with these agents. For those wishing to learn the subject de novo, a good introductory book chapter in a toxicology or emergency medicine text would be better. But this is a very good refresher for those already comfortable with osmolal and anion gaps, alcohol dehydrogenase inhibitors, and indications for hemodialysis in these poisonings. 80 up-to-date references. Related posts: Hemodialysis in acute methanol poisoning: is there really good evidence? NEJM discussion of ethylene glycol poisoning misses important points Can hemodialysis be avoided in selected patients with significant serum levels of ethylene glycol? Use of fomepizole in pediatric poisonings Tox Tunes #12: Canned Heat Blues (Tommy Johnson) Central pontine myelinolysis associated with ethylene glycol intoxication Snow White and ethylene glycol — or was it really diethylene glycol? Do all patients with significantly elevated ethylene glycol levels need to be dialyzed? Ethylene glycol, murder, and the media 154 admissions for ethylene glycol poisoning — in the same patient! Severe ethylene glycol toxicity ...
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical diethylene glycol isopropanol methanol propylene glycol Review toxic alcohol Source Type: news