Epothilone D accelerates disease progression in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis

ConclusionsThe results suggest that EpoD accelerates disease progression in the SOD1G93A mouse model of ALS, and highlights that the pathophysiological involvement of microtubules in ALS is an evolving and underappreciated phenomenon.This article is protected by copyright. All rights reserved.

Source: Neuropathology and Applied Neurobiology - December 1, 2017 Category: Neurology Authors: Jayden A. Clark, Catherine A. Blizzard, Monique C. Breslin, Elise J. Yeaman, Ka M. Lee, Jyoti A. Chuckowree, Tracey C. Dickson Tags: Original Article Source Type: research