Pleuroparenchymal fibroelastosis after haematopoietic stem cell transplantation without graft ‐versus‐host disease findings

We report the case of a patient with PPFE after HSCT. The patient experienced pneumothorax repeatedly despite surgical treatment. A surgical specimen demonstrated PPFE findings, without evidence of GVHD. In this case, development of PPFE was not associated with GVHD, and immunosuppressive therapy did not improve pulmonary function. Surgical biopsy is recommended for precise treatment and elucidation of pathogenesis in each suspected PPFE patient. We report the case of a patient with pleuroparenchymal fibroelastosis (PPFE) after haematopoietic stem cell transplantation (HSCT). A surgical specimen showed PPFE findings, without evidence of graft‐versus‐host disease (GVHD). In this case, development of PPFE was not associated with GVHD.
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research