Pseudomalignant osteoblastoma of the odontoid process

ConclusionThis unique case of odontoid osteoblastoma illustrates that malignant behavior may not be predicted only by the presence of pseudomalignant features on histology.
Source: European Spine Journal - Category: Orthopaedics Source Type: research

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ConclusionSclerosis can occur in endplates with any type of MCs. However, the clinical and animal study suggests that sclerosis is greatest in endplates showing type III MCs.The translational potential of this articleThe study showed that sclerosis can occur in endplates with MCs type I, II and III. In patients with endplate sclerosis on plain radiographs or CT scans, the endplate can still represent an inflammatory process associated with chronic lower back pain.
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research
American physicians dole out lots of unnecessary medical care to their patients. They prescribe things like antibiotics for people with viral infections, order expensive CT scans for patients with transitory back pain, and obtain screening EKGs for people with no signs or symptoms of heart disease. Some critics even accuse physicians of ordering such services to bolster their revenue. So what happens when uninsured patients make it to the doctor’s office with coughs, low back pain, or other problems? Do physicians stop ordering all these unnecessary tests and services, out of recognition that most of these patients w...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Policy Medicare Public Health & Source Type: blogs
Scandinavian Journal of Caring Sciences, EarlyView.
Source: Scandinavian Journal of Caring Sciences - Category: Nursing Authors: Source Type: research
​BY LAURIE-ANN​ ANTOINE; MOHIT S. MAHALAN; &AHMED RAZIUDDIN, MDA 32-year-old afebrile woman presented to the emergency department in acute distress from abdominal pain, which she described as severe and crampy. The pain had begun approximately six hours prior to her visit to the hospital, and was associated with nausea and intractable, bilious vomiting. The patient consumed one dose of liquid bismuth subsalicylate, but it did not provide relief.The patient's last bowel movement was several hours prior to her arrival at the hospital and was nonbloody. Her past medical and surgical history were unremarkable. The pati...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
CONCLUSIONS: Denosumab has substantial activity in ABCs, with favorable toxicity profile. We strongly support the use of surgery and/or embolization for the treatment of ABC, but denosumab could have a role as a therapeutic option in patients with uncontrollable, locally destructive, or recurrent disease. PMID: 30086700 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
MD+DI has been tracking miniaturization for some time, as we’ve seen trends deepen in minimally invasive surgeries, wearable devices, advanced drug delivery, and more. Lindsay Mann, director of marketing for MTD Micro Molding, tells MD+DI that about 25% of the micro medical device components they produce are for miniaturized devices. We asked her for an update on miniaturization, including recent advancements in materials and manufacturing.   What is driving the current trend toward medical device miniaturization? Mann: As less invasive procedures and technology-driven advancements...
Source: MDDI - Category: Medical Devices Authors: Tags: MD & M Minneapolis Molding Source Type: news
In this study, we analyzed FGF21 levels and alterations in the expression of genes encoding components of the FGF21-responsive molecular machinery in adipose tissue from aged individuals so as to ascertain whether altered FGF21 responsiveness that develops with aging jeopardizes human health and/or accelerates metabolic disturbances associated with aging. We studied a cohort of 28 healthy elderly individuals (≥70 years) with no overt signs of metabolic or other pathologies and compared them with a cohort of 35 young healthy controls (≤40 years). Serum FGF21 levels were significantly increased in elderly indiv...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
UCLA Health Rhianna Wilson spent her senior year of high school in and out of four San Diego hospitals, seeking relief for her vision loss, leg pain and excruciating  headaches.At 18, she was diagnosed with Ehler-Danlos Syndrome, a rare genetic disorder marked by overly stretchy connective tissue. In Rhianna ’s case, the disorder revealed itself in double-jointedness that led to four shoulder dislocations.An MRI showed that Wilson had a small slippage of her brain into her spinal column, called a Chiari malformation. The lower part of Wilson ’s brain drooped exactly five millimeters below her skull, p...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Conclusion. This study provides histologic basis for a system to classify focal endplate irregularities. Included is a previously unidentified but prevalent finding of tidemark avulsions, which are visible with both histology and magnetic resonance imaging. These observations will help clinicians better organize patients into meaningful groups to facilitate diagnosis, treatment, and clinical research. Level of Evidence: 3
Source: Spine - Category: Orthopaedics Tags: Anatomy Source Type: research
Conclusion Patients who present with symptoms consistent with Bertolotti's syndrome, even if they have a type III or type IV LSTV, should be considered for surgical treatment of their LSTV. These patients can respond well, even if symptoms have been present for years. Given the prevalence of these anatomic variants in the general population (10–12% in most series), Bertolotti's syndrome should be considered in the differential diagnosis of any patient with a presentation of L5 radiculopathy and/or back pain. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents&nb...
Source: Journal of Neurological Surgery Reports - Category: Neurosurgery Authors: Tags: Case Report Source Type: research
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