Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds.

Conclusion: All women in breast or breast/ovarian cancer kindreds would benefit from being offered genetic testing irrespective of which causative genetic variants have been demonstrated in their relatives. PMID: 29371908 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/29371908?dopt=Abstract

Source: Clinical Breast Cancer - January 28, 2018 Category: Cancer & Oncology Authors: Dominguez-Valentin M, Evans DGR, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E Tags: Hered Cancer Clin Pract Source Type: research