Rasagiline delays retinal degeneration in a mouse model of retinitis pigmentosa via modulation of Bax/Bcl-2 expression.

CONCLUSION: This study provides new evidences regarding the neuroprotective effect of rasagiline in the retina, and it brings new insight into the development of future clinical trials using this well-established antiparkinsonian drug to treat RP.
PMID: 29372592 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - January 25, 2018 Category: Neuroscience Authors: Garcia-Delgado AB, Valdés-Sánchez L, Calado SM, Diaz-Corrales FJ, Bhattacharya SS Tags: CNS Neurosci Ther Source Type: research