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Study: Hospital Patients Still More Likely To Die On Weekends

By Michael Nedelman, CNN (CNN) — Doctors call it the “weekend effect.” Patients in the hospital are more likely to die off-hours — whether it’s due to a brain bleed, a heart attack or a clot in the lungs. New research on cardiac arrest in the hospital now asks: Has the “weekend effect” changed in recent years, as treatment has gotten better? “We know that survival trends have improved in past decade or so,” said Dr. Uchenna Ofoma, assistant professor of medicine at Temple University and a critical care physician at Geisinger Health System in Danville, Pennsylvania. “The question now becomes … what happens to the disparities? Has it remained the same? Is it narrowing?” Ten years after a 2008 study showed lower survival rates during nights and weekends for in-hospital cardiac arrest, Ofoma published a new study this week in the Journal of the American College of Cardiology. The new study builds on that previous research, finding that treatment has indeed gotten better, but we haven’t closed the nights-and-weekends gap. Between 2000 and 2014, weekday survival jumped from 16% to 25.2%, while weekend and weeknight survival rose from 11.9% to 21.9%, according to the new study’s risk-adjusted numbers. There was no significant change in the gap between weekday and off-hours survival, the study said. About half of patients in the study — more than 150,000 patients from 470 US hospitals — e...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News cardiac arrest Source Type: news

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Authors: Siennicka A, Jastrzebska M, Smialkowska K, Oledzki S, Chelstowski K, Klysz M, Clark J, Kornacewicz-Jach Z Abstract Many studies have shown gender differences in the progress of acute coronary syndromes (ACS). These differences include, amongst others, processes involved in hemostasis and inflammation, and in the present study we put forward the hypothesis that these are the primary cause of other differences. The study included 66 ACS patients (27 women and 39 men) aged 43 - 83 years, 23 with non-ST-elevation myocardial infarction (NSTEMI) and 43 with ST-elevation myocardial infarction (STEMI). Blood sampl...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Management of peridural catheter removal during dual anti-platelet therapy after postoperative myocardial infarction and drug-eluting stent implantation, applying the "bridging therapy" concept. Minerva Anestesiol. 2018 May 15;: Authors: Mogavero T, Pace R, Vetrugno L PMID: 29774732 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
CONCLUSIONS: In ACS patients, the rates of MACE and NACE were not significantly lower with bivalirudin than with UFH in both sexes.The rate of the composite of urgent TVR,definite ST,or NACE was not significantly lower with a post-PCI bivalirudin infusion than with no post-PCI infusion in both sexes. PMID: 29769167 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Conclusions: Galectin-3 is directly associated with early myocardial inflammation post-MI and may represent a potential target for therapeutic inhibition. PMID: 29769800 [PubMed]
Source: Biomarker Insights - Category: General Medicine Authors: Tags: Biomark Insights Source Type: research
Three-dimensional echocardiography in the diagnosis of myocardial infarction and its correlation with the expressions of serum HIF-1α, HO-1 and VEGF. Eur Rev Med Pharmacol Sci. 2018 May;22(9):2751-2756 Authors: Yu Q, Li L, Zhao N Abstract OBJECTIVE: To investigate the correlation between three-dimensional echocardiography and the expressions of hypoxia-inducible factor-1 alpha (HIF-1α), heme oxygenase 1 (HO-1) and vascular endothelial growth factor (VEGF) in patients with myocardial infarction. PATIENTS AND METHODS: A total of 40 patients with acute myocardial infarction treated with th...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
In patients with suspected ST elevation myocardial infarction, it is of paramount importance to identify artifacts on the resting electrocardiogram that may be erroneously interpreted as ST segment deviations in order to prevent administration of potentially harmful pharmacotherapy and invasive coronary angiography. In this case report, we describe a pervasive square wave artifact, not previously reported, that was misdiagnosed as ST segment elevation by computer software and initial physician interpretation.
Source: Journal of Electrocardiology - Category: Cardiology Authors: Source Type: research
AbstractCurrent guidelines recommend that percutaneous coronary intervention (PCI) should be restricted to the culprit vessel in ST elevation myocardial infarction (STEMI) patients with multi-vessel disease (MVD) and without cardiogenic shock. However, newer data suggests that performing complete revascularization (CR) in MVD patients may lead to better outcomes compared to intervention in the culprit vessel only. The aim of this meta-analysis is to examine the available data to determine if CR (using either angio- or fractional flow reserve guidance —FFR) following primary PCI in STEMI patients without cardiogenic s...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
ConclusionsThe risk of the composite outcome of death, MI, stroke, or major bleeding at 2-year follow-up was significantly higher in TAVR patients treated with TT or SAC versus AP, even after multivariate adjustment.
Source: Cardiology and Therapy - Category: Cardiology Source Type: research
Conclusions Impaired LV strain overestimates nonviable myocardium compared with TMI on LGE. Ischemia and infarct proximity also decrease strain in viable segments.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Despite advances in therapy, coronary artery disease (CAD) and myocardial infarction (MI) are leading causes of mortality in western societies and identification of patients at risk in clinical routine remains challenging [1].
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
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