Study: Hospital Patients Still More Likely To Die On Weekends

By Michael Nedelman, CNN (CNN) — Doctors call it the “weekend effect.” Patients in the hospital are more likely to die off-hours — whether it’s due to a brain bleed, a heart attack or a clot in the lungs. New research on cardiac arrest in the hospital now asks: Has the “weekend effect” changed in recent years, as treatment has gotten better? “We know that survival trends have improved in past decade or so,” said Dr. Uchenna Ofoma, assistant professor of medicine at Temple University and a critical care physician at Geisinger Health System in Danville, Pennsylvania. “The question now becomes … what happens to the disparities? Has it remained the same? Is it narrowing?” Ten years after a 2008 study showed lower survival rates during nights and weekends for in-hospital cardiac arrest, Ofoma published a new study this week in the Journal of the American College of Cardiology. The new study builds on that previous research, finding that treatment has indeed gotten better, but we haven’t closed the nights-and-weekends gap. Between 2000 and 2014, weekday survival jumped from 16% to 25.2%, while weekend and weeknight survival rose from 11.9% to 21.9%, according to the new study’s risk-adjusted numbers. There was no significant change in the gap between weekday and off-hours survival, the study said. About half of patients in the study — more than 150,000 patients from 470 US hospitals — e...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News cardiac arrest Source Type: news

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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ConclusionsThe current study indicates that a history of OSAS/CSAS, myocardial infarction and BMI > 30 might be related to ICU admission in influenza patients. Second, ICU patients develop more pulmonary co-infections. Last, (pre-existent) renal failure and diabetes mellitus are more often observed in non-survivors.
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research
Authors: Rey F, Ronchard T, Chaara J, Noble S Abstract PMID: 30430807 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
HOW to live longer: Avoid an early death by eating healthy, balanced diet, and by doing regular exercise. You could increase your life expectancy by eating this cheap “wonderfood”. It could even lower your risk of heart attacks.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
This study included 172 consecutive patients with their first acute MI, 88 STEMI, and 84 NSTEMI, treated with PCI. On the third day of hospitalization, blood samples were collected from each patient to measure the concentration of clopidogrel and its metabolite 2-oxo-clopidogrel using the UHPLC-DAD-MS method. The following clinical outcomes were registered during the 28-month follow-up: mortality from cardiovascular causes, nonfatal MI, nonfatal stroke, and hospitalization for urgent myocardial revascularization or heart failure. RESULTS: Lower dose-adjusted clopidogrel concentrations (p 
Source: International Journal of Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research
This article describes the process of performing a computed tomography scan for coronary artery calcium, quantifying the score and interpreting the results.
Source: Radiologic Clinics of North America - Category: Radiology Authors: Source Type: research
In the United Kingdom, around 56,000 patients with angina, a chest condition that can decrease blood flow to the heart, were unable to undergo necessary CT scans last year due to the region ’s radiologist shortage.According to a recent review from the Royal College of Radiologists (RCR) and the British Society of Cardiovascular Imaging (BSCI), there should have been 132,090 CT coronary angiography (CTCA) tests performed throughout England, Scotland, Wales, and Northern Ireland in 2017. However, only 75,791 —or 57 percent — of those tests were administered.Approximately 69,900 scans were performed in Engla...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
CONCLUSIONS: PA use may reduce initial stroke severity in AT stroke and the risk of END, and can improve functional outcome at three months irrespective of stroke subtypes. PMID: 30429408 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Expression profile of long non‑coding RNAs in cardiomyocytes exposed to acute ischemic hypoxia. Mol Med Rep. 2018 Nov 13;: Authors: Li H, Cheng Z, Tang Y, Feng M, Yin A, Zhang H, Xu J, Zhang Q, Zhang J, Qian L Abstract Acute myocardial infarction (AMI) is a life‑threatening disease and seriously influences patient quality of life. Long non‑coding RNAs (lncRNAs), an emerging class of non‑coding genes, have attracted attention in research, however, whether lncRNAs serve a function in acute ischemic hypoxia remains to be elucidated. In the present study, an lncRNA microarray was used to analyze di...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
ConclusionHg exposure could trigger epigenetic alterations, hence leading to various human disorders including reduced newborn cerebellum size, adverse behavioral outcomes, atherosclerosis and myocardial infarction. Similarly, in adults, occupational Hg exposure has been associated with an increased risk of autoimmunity. It has been revealed that miRNAs in the woman’s cervix are a novel responder to maternal Hg exposure during pregnancy. Hg-induced epigenetic alterations analysis of kidney tissues showed a significant interruption in renal function. DNA methylation and histone post-translation modifications are predo...
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
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