Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome.

This study revealed that obesity increases survival in animals with myelodysplastic syndrome. This may be due to the greater fat mass of Ob/Ob mice, which acts as a sink for myeloid cells, preventing their accumulation in other key organs such as the liver. PMID: 29371326 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29371326?dopt=Abstract

Source: Haematologica - January 25, 2018 Category: Hematology Authors: Kraakman MJ, Kammoun HL, Dragoljevic D, Al-Sharea A, Lee MKS, Flynn MC, Stolz CJ, Guirguis AA, Lancaster GI, Chin-Dusting J, Curtis DJ, Murphy AJ Tags: Haematologica Source Type: research