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Breast Cancer Stage at Diagnosis in a New Jersey Cancer Education and Early Detection Site.

This study will provide a first snapshot of the effectiveness of the New Jersey program, by comparing stage at diagnosis for enrollees as compared with nonenrollees who received definitive treatment for breast cancer at the same academic medical center. MATERIALS AND METHODS: A retrospective analysis of 5 years of breast cancer data abstracted from the Cancer Registry of a large urban hospital in the Northeast United States. Bivariate analysis and logistic regression were utilized. RESULTS: One thousand forty women were screened for and diagnosed with breast cancer at this site; they were more likely to be racially (P
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Am J Clin Oncol Source Type: research

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Authors: Suh DH, Kim M, Lee KH, Eom KY, Kjeldsen MK, Mirza MR, Kim JW Abstract In 2017, 10 topics were selected as major clinical research advances in gynecologic oncology. For cervical cancer, efficacy and safety analysis results of a 9-valent human papillomavirus (HPV) vaccine and long-term impact of reduced dose of quadrivalent vaccine were updated. Brief introduction of KEYNOTE trials of pembrolizumab, a monoclonal antibody that blocks the interaction between programmed death (PD)-1 and its ligands, PD-L1 and PD-L2, followed. Tailored surveillance programs for gynecologic cancer related with Lynch syndrome and ...
Source: Journal of Gynecologic Oncology - Category: OBGYN Tags: J Gynecol Oncol Source Type: research
[Independent (Kampala)] Kampala -As early as 9am on Feb.09, people had started gathering at Centenary Park. It was yet another 'free medical camp'. Organized by the Mulago hospital based College of Health Sciences, people would at this camp get free checkups for cervical cancer, breast cancer, hypertension and dental care among others. Organisers of the camp were just starting to hang the banners and set up tables but people were already queuing. I sensed it could get crowded.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Publication date: Available online 17 February 2018 Source:Journal of Cancer Policy Author(s): Tingting Xu, Jing Wu Cancer is not only a medical problem, but also a socio-economical issue as the high prevalence with poor prognosis brings heavy financial burden to the society. From 2005 to 2013, the incidence and mortality rates have sharply increased in China. The most common types of cancer in males in China are lung cancer, gastric cancer, liver cancer, colorectal cancer and esophageal cancer while breast cancer, lung cancer, colorectal cancer, gastric cancer, and cervical cancer are the major types of cancer among Chin...
Source: Journal of Cancer Policy - Category: Cancer & Oncology Source Type: research
Abstract Previous studies have showed the associations between various BRCA1-interacting protein 1 (BRIP1) polymorphisms and cancer risk. But, these results were inconsistent. This meta-analysis based on 18 studies involving 13,716 cancer patients and 15,590 cancer-free controls is aimed at to evaluate the relationship between the four common SNPs of BRIP1 (rs2048718, rs4988344, rs4986764, and rs6504074) and cancer risk. The results showed a decreased risk of rs2048718 or rs4986764 for cervical cancer rather than breast cancer in the overall population (P
Source: Aging - Category: Biomedical Science Authors: Tags: Aging (Albany NY) Source Type: research
Abstract Regioisomers of the functional group of the main ligand (L) on a series of [Ru(phen)2L]2+and [Ru(bpy)2L]2+ complexes, where phen is 1,10 phenanthroline and bpy is 2,2'-bipyridine, were synthesised to investigate the interaction with deoxyribonucleic acid (DNA) as potential therapeutics. UV-Vis binding titrations, thermal denaturation and circular dichroism were used to evaluate their interaction with DNA. The conclusions indicated the significance of the auxiliary ligand; especially 1,10-phenanthroline has on the binding constants (Kb). The systematic variation of auxiliary ligand(phen or bpy), and polypy...
Source: Journal of Inorganic Biochemistry - Category: Biochemistry Authors: Tags: J Inorg Biochem Source Type: research
[The Herald] Firsty Lady Auxillia Mnangagwa was yesterday screened for cervical and breast cancer at United Bulawayo Hospitals (UBH) as a way of motivating women to do the same as the country intensifies the fight against the silent killer.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Excerpted fromPrecision Medicine and the Reinvention of Human DiseaseDespite having the most advanced healthcare technology on the planet, life expectancy in the United States is not particularly high. Citizens from most of the European countries and the highly industrialized Asian countries enjoy longer life expectancies than the United States. According to the World Health Organization, the United States ranks 31st among nations, trailing behind Greece, Chile, and Costa Rica, and barely edging out Cuba [42]. Similar rankings are reported by the US Central Intelligence Agency [43]. These findings lead us to infer that acc...
Source: Specified Life - Category: Information Technology Tags: cancer cancer vaccines precision medicine prevention public health Source Type: blogs
[Daily News] WHILE national records cite cervical cancer as the second most troublesome disease in Tanzania behind breast cancer, the Aga Khan hospital has slotted colorectal cancer in the position.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Conclusion Alpelisib demonstrated a tolerable safety profile and encouraging preliminary activity in patients with PIK3CA-altered solid tumors, supporting the rationale for selective PI3Kα inhibition in combination with other agents for the treatment of PIK3CA-mutant tumors. PMID: 29401002 [PubMed - as supplied by publisher]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: J Clin Oncol Source Type: research
AbstractIn order to find new anticancer drugs, a series of novel furoxan-based coumarin derivatives (10a–k) were synthesized and evaluated for their antiproliferative activities in vitro. All compounds displayed more potent inhibition on human cervical cancer HeLa cell proliferation than coumarin-3-carboxylic acid, and compounds10b, 10c, 10f, 10h, and10i with IC50 values ranging from 0.88 to 5.95  μM were even stronger than doxorubicin (IC50 = 10.21 μM). The further study showed that compound10i exerted the highest antiproliferative activity (IC50 = 0.60 μM) a...
Source: Medicinal Chemistry Research - Category: Chemistry Source Type: research
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