Meox1 accelerates myocardial hypertrophic decompensation through Gata4

ConclusionMeox1 accelerated decompensation via the downstream target Gata4, at least in part directly. Meox1 and other foetal programme genes form a highly interconnected network, which offers multiple therapeutic entry points to dampen the aberrant expression of foetal genes and pathological hypertrophy.
Source: Cardiovascular Research - Category: Cardiology Source Type: research