Influence of TBX21 T-1993C variant on autoimmune hepatitis development by Yin-Yang 1 binding.

CONCLUSION: The repression of TBX21 expression by high-affinity binding of YY1 to the -1993C allele may contribute to a decreased development of AIH-1 via suppression of type 1 immunity.
PMID: 29358858 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - December 28, 2017 Category: Gastroenterology Authors: Sun W, Wu HY, Chen S Tags: World J Gastroenterol Source Type: research