Women with polycystic ovary syndrome have less bacterial diversity in gut
(University of California - San Diego) Women who have polycystic ovary syndrome (PCOS), a common hormone condition that contributes to infertility and metabolic problems, such as diabetes and heart disease, tend to have less diverse gut bacteria than women who do not have the condition, according to researchers at University of California San Diego School of Medicine, in collaboration with colleagues at Poznan University of Medical Sciences in Poland and San Diego State University.
Conclusions: We did not find any impact of brain atrophy on the risk of END and the outcome at 3 months in severe ischemic strokes after IV thrombolysis.Eur Neurol 2018;79:240 –246
CONCLUSION: The finding of a family risk of developing plurimetabolic syndrome and a diagnosis of rheumatic heart disease indicates that patients with oral clefts may be more prone to developing acquired heart disease. Thus, our findings highlight the importance of anamnesis and methodological triangulation (clinical-electrocardiographic-echocardiographic) in the investigation of patients with oral clefts and emphasize that cardiological follow-up to evaluate acquired and/or rhythm heart diseases is necessary. This strategy permits comorbidity prevention and individualized planned treatment.
The American physician and writer, Danielle Ofri, tells the story of a near fatal mistake that she made at the beginning of the second year of her residency. A patient was brought to the emergency room in a diabetic coma, and although her initial management was fine, Ofri then made an error and “proceeded to nearly kill…[the] patient”. Recognising her predicament, she called for senior assistance. When an explanation was demanded of her performance, Ofri's words dried up. Humiliation set in as she was questioned in front of her intern: “I could almost feel myself dying away on the spot.
Public health physician and champion of women in medicine. She was born in Derry, UK, on Sept 2, 1929, and died with heart disease and dementia in London, UK, on Jan 20, 2018, aged 88 years.
Conclusion: Paricalcitol and D/P creatinine were independently related to PPL. Paricalcitol may have an effect on PPL in PD patientsBlood Purif 2018;46:103 –110
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in adult women (1). It can't be cured, but thanks to many years of fruitful research and intensive investigation, multiple modalities to help manage the condition throughout a woman's lifetime have emerged. Those of us who have been in practice for more than a decade or two have likely had the experience of managing mothers and daughters with the condition. Many of us have supported our PCOS patients through an adolescence complicated by acne and hair growth, an early adulthood complicated by infertility and irregular menses, and late reproductive age compl...
Polycystic ovary syndrome (PCOS) is a highly inheritable complex genetic trait and one of the most prevalent endocrine-metabolic-reproductive disorders of humans, clinically evident in 10% –15% of reproductive-age women. It is the single most common cause of ovulatory infertility in women and of subfertility overall in Western societies. Fundamentally, most patients with PCOS, particularly those with hyperandrogenic phenotypes, also demonstrate underlying metabolic dysfunction and s ubclinical chronic inflammation, leading to insulin resistance and compensatory hyperinsulinemia.
Authors: Liu K, Motan T, Claman P Abstract OBJECTIVES: To review the etiology, evaluation, and treatment of hirsutism. EVALUATION: A thorough history and physical examination plus selected laboratory evaluations will confirm the diagnosis and direct treatment. TREATMENT: Pharmacologic interventions can suppress ovarian or adrenal androgen production and block androgen receptors in the hair follicle. Hair removal methods and lifestyle modifications may improve or hasten the therapeutic response. OUTCOMES: At least 6 to 9 months of therapy are required to produce improvement in hirsutism. EVIDENCE: Th...
DiscussionPolycystic ovary syndrome (PCOS) affects 6-8% of reproductive-age women making it the most common endocrinopathy in this age group. There is no consensus on the specific diagnostic criteria for PCOS in adolescents as many of the characteristics overlap with normal adolescent physiology. However, patients should have evidence of hyperandrogenism, oligo- or amenorrhea, and potentially polycystic ovaries. PCOS has a genetic component although a specific gene has not been identified. Incidence of PCOS is 20-40% for a woman with a family history. Hyperandrogenism Androgen levels change during puberty therefore actual ...
(The Endocrine Society) Women who have polycystic ovary syndrome -- a common cause of female infertility -- may be able to improve their metabolic and cardiovascular health by consuming soy isoflavones, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology&Metabolism.