Modeling of Normal Tissue Complications Using Imaging and Biomarkers After Radiation Therapy for Hepatocellular Carcinoma.
CONCLUSIONS: The incorporation of imaging findings and biological markers into NTCP modeling of liver toxicity improved the estimates of expected NTCP risk compared with using dose-only models. In addition, such generalized NTCP models should contribute to a better understanding of the normal tissue response in HCC SBRT patients and facilitate personalized treatment.
PMID: 29353652 [PubMed - in process]
Source: Physics in Medicine and Biology - Category: Physics Authors: El Naqa I, Johansson A, Owen D, Cuneo K, Cao Y, Matuszak M, Bazzi L, Lawrence TS, Ten Haken RK Tags: Int J Radiat Oncol Biol Phys Source Type: research
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