Acute kidney injury: Antioxidants do not PRESERVE kidney function after contrast exposure

Acute kidney injury: Antioxidants do not PRESERVE kidney function after contrast exposureAcute kidney injury: Antioxidants do not PRESERVE kidney function after contrast exposure, Published online: 22 January 2018; doi:10.1038/nrneph.2017.185New data from the PRESERVE trial suggest that administration of N-acetylcysteine and/or sodium bicarbonate does not reduce the incidence of acute kidney injury in patients with chronic kidney disease undergoing angiography. Given the limitations of this study, use of these antioxidants should be considered discretionary until further data becomes available.

Source: Nature Reviews Nephrology - January 22, 2018 Category: Urology & Nephrology Authors: Richard Solomon Source Type: research