Overnight auto-adjusting continuous airway pressure  + standard care compared with standard care alone in the prevention of morbidity in sickle cell disease phase II (POMS2b): study protocol for a randomised controlled trial

DiscussionAltering oxygen saturation in HbSS may lead to bone marrow suppression. This risk will be reduced by monitoring full blood counts at baseline, two weeks, three months and six months, providing treatment as appropriate and reporting as safety events.Trial registrationISRCTN46012373. Registered on 10 July 2015.Protocol Version: 6.0 Date: 24th December 2015Sponsor: University Hospital Southampton. Sponsor ’s protocol code: RHMCHIOT53
Source: Trials - Category: Research Source Type: clinical trials