Laparoscopic gastric bypass with remnant gastrectomy in a super-super obese patient with gastric metaplasia: a surgical hazard?

We present the case of a 55-year-old super-super obese man with a family history of GC and antral gastritis with extensive intestinal metaplasia at preoperative upper endoscopy, who underwent laparoscopic RYGBP with remnant gastrectomy. PMID: 29350665 [PubMed - in process]
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Tags: Acta Biomed Source Type: research

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CONCLUSIONS: Specific signs and symptoms, chronic conditions, a greater comorbidity burden, and specific pharmacological treatments registered in primary care databases represent relevant predictors and correlates of incident IDA in older people in Europe. General practitioners might employ this information to obtain early diagnosis of IDA in community-dwelling older adults. PMID: 31893385 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Tags: Aging Clin Exp Res Source Type: research
Background: Insulin resistance, the primary mechanism of metabolic syndrome, promotes gastric carcinogenesis. Metabolic syndrome is associated with sarcopenia. We aimed to investigate the association between sarcopenia and gastric carcinogenesis, including precancerous conditions such as atrophic gastritis (AG), intestinal metaplasia (IM), and dysplasia.Methods: The study included adult patients who underwent gastroduodenoscopy at a checkup center. AG and IM were evaluated using endoscopy. Based on muscle mass, sarcopenia was defined as a skeletal muscle index
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Gastric cancer (GC) begins development in the mucus-producing cells which line the stomach [1]. Approximately 90 to 95% of all GCs are adenocarcinoma [6]. Since the middle of the 20th century, the incidence and mortality rates of GC in high-income countries of Europe and North America have been declining [13]. While there are many risk factors for the development of gastric cancer, such as Helicobacter pylori infection, chronic gastritis, pernicious anemia, intestinal metaplasia, gastric polyps, smoking, or having a family history of GC [11], obesity has not been named a risk.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
AbstractHelicobacter pylori (H. pylori) infection is a common disease that can cause chronic gastritis, peptic ulcers, and gastric cancer. Nevertheless, due to its ability to elicit a systemic inflammatory response, it has also been related to several extra-gastric manifestations including endocrine disorders, such as autoimmune thyroid diseases, diabetes mellitus, dyslipidemia, and obesity.H. pylori infection has also been linked to osteoporosis, although currently available data are equivocal. This brief review will focus on the possible association betweenH. pylori infection and osteoporosis, a silent disease characteri...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
AbstractIn the West, the incidence of esophageal adenocarcinoma, which is a long-term complication of damage by gastroesophageal reflux, has been rising over recent decades. Two main factors are likely to account for this increase. The first is the rising incidence of central obesity which promotes gastroesophageal reflux. The second is the falling incidence ofH. pylori infection and associated atrophic gastritis which reduces the acidity and peptic activity of gastric juice, the main factors damaging to the esophageal mucosa. The rise in esophageal adenocarcinoma has been mirrored by a fall in gastric cancer consistent wi...
Source: Journal of Gastroenterology - Category: Gastroenterology Source Type: research
In this study, the gut microbiota of 30 LC patients and 30 healthy controls were examined via next-generation sequencing of 16S rRNA and analyzed for diversity and biomarkers. We found that there was no decrease in significant microbial diversity (alpha diversity) in LC patients compared to controls (P observed = 0.1422), while the composition (beta diversity) differed significantly between patients and controls (phylum [stress = 0.153], class [stress = 0.16], order [stress = 0.146], family [stress = 0.153]). Controls had a higher abundance of the bacterial phylum Actinobacteria and genus Bifidobacterium, while patients wi...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
ConclusionWhen confounders were taken into account, there appeared no significant associations between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies of their gastric specimens. There was a very weak correlation between BMI and other covariates.
Source: Obesity Surgery - Category: Surgery Source Type: research
Publication date: February 2019Source: Journal of Functional Foods, Volume 53Author(s): Yogendra Prakash Singh, Sosmitha Girisa, Kishore Banik, Sharad Ghosh, Pantheerayil Swathi, Manab Deka, Ganesan Padmavathi, Jibon Kotoky, Gautam Sethi, Lu Fan, Xinliang Mao, Clarissa Esmeralda Halim, Frank Arfuso, Ajaikumar B. KunnumakkaraAbstractSeveral active compounds from ‘Mother Nature’ have been found to be tailor-made therapeutics for the better management of numerous chronic ailments, with fewer adverse side effects. Zerumbone is one such molecule isolated from the rhizomes of Zingiber zerumbet (L.) Smith, a Zingibera...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
ConclusionsRoutine UGE may be necessary before bariatric procedures in obese Japanese patients.
Source: Surgery Today - Category: Surgery Source Type: research
Abstract Helicobacter pylori (Hp) is a major human pathogen causing chronic, progressive gastric mucosal damage and is linked to gastric atrophy and cancer. Hp-positive individuals constitute the major reservoir for transmission of infection. There is no ideal treatment for Hp. Hp infection is not cured by a single antibiotic, and sometimes, a combined treatment with three or more antibiotics is ineffective. Atrophic gastritis (AG) is a chronic disease whose main features are atrophy and/or intestinal metaplasia of the gastric glands, which arise from long-standing Hp infection. AG is reportedly linked to an incre...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
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