Macrophage Transitions in Heart Valve Development and Myxomatous Valve Disease.

CONCLUSIONS: Our study demonstrates the heterogeneity of myeloid cells in heart valves and highlights an alteration of macrophage subpopulations, notably an increased presence of infiltrating CCR2+ monocytes and CD206+ macrophages, in myxomatous valve disease.
PMID: 29348122 [PubMed - as supplied by publisher]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - January 18, 2018 Category: Cardiology Authors: Hulin A, Anstine LJ, Kim AJ, Potter SJ, DeFalco T, Lincoln J, Yutzey KE Tags: Arterioscler Thromb Vasc Biol Source Type: research