Genetic Background of Iris Melanomas and Iris Melanocytic Tumors of Uncertain Malignant Potential

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Iris melanoma comprises 4% to 10% of all UMs and has a lower mortality rate. The genetic changes in iris melanoma are not as well characterized as ciliary body or choroidal melanoma. The aim of this study was to gain more insight into the genetic background of iris melanoma and iris nevi.

Source: Ophthalmology - January 19, 2018 Category: Opthalmology Authors: Natasha M. van Poppelen, Jolanda Vaarwater, Hardeep S. Mudhar, Karen Sisley, Ian G. Rennie, Paul Rundle, Tom Brands, Quincy C.C. van den Bosch, Hanneke W. Mensink, Annelies de Klein, Emine Kili ç, Robert M. Verdijk Source Type: research