Should STEMI Patients Receive Opiate Analgesia? The Morphine Paradox.

CONCLUSION: Whilst clearly definitive, adequately powered, randomised controlled trials are lacking, we would recommend avoiding the combination of morphine with oral P2Y12 receptor inhibitors and recommend alternative strategies including intravenous platelet inhibitor strategies, in high risk patients. PMID: 29345594 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29345594?dopt=Abstract

Source: Current Vascular Pharmacology - January 17, 2018 Category: Drugs & Pharmacology Authors: Farag M, Spinthakis N, Srinivasan M, Gorog DA Tags: Curr Vasc Pharmacol Source Type: research