Jan 19, 2018 This Week in Cardiology

MRI in patients with cardiac devices, bariatric surgery, statins, the LifeVest wearable defibrillator, and spontaneous coronary dissection are the topics discussed in this week's podcast.
Source: Medscape Cardiology Podcast - Category: Cardiology Authors: Source Type: podcasts

Related Links:

Conclusions: While there is a certain overlap between the results of the current study and published transcriptomic profiles of non-transplanted livers with steatosis, we have identified discrete characteristics of the non-alcoholic fatty liver disease in liver grafts potentially utilizable for the establishment of predictive signature. Introduction Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in industrialized countries, its prevalence being estimated at 19–31.3% (1). It encompasses a range of conditions that are thought to arise from fatty liver (simple steatosis) throu...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Authors: Malmasi S, Hosomura N, Chang LS, Brown CJ, Skentzos S, Turchin A Abstract Healthcare quality research is a fundamental task that involves assessing treatment patterns and measuring the associated patient outcomes to identify potential areas for improving healthcare. While both qualitative and quantitative approaches are used, a major obstacle for the quantitative approach is that many useful healthcare quality indicators are buried within provider narrative notes, requiring expensive and laborious manual chart review to identify and measure them. Information extraction is a key Natural Language Processing ...
Source: AMIA Annual Symposium Proceedings - Category: Bioinformatics Tags: AMIA Annu Symp Proc Source Type: research
Conclusion: The TEMD Obesity Study shows that obesity is a major determinant of the poor metabolic control in patients with type 2 diabetes. These results underline the importance of prevention and management of obesity to improve health care in patients with type 2 diabetes. Also, the results point out the independent sociodemographic and clinical associates of obesity, which should be the prior targets to overcome, in the national fight with obesity.Obes Facts 2019;12:167 –178
Source: Obesity Facts - Category: Eating Disorders & Weight Management Source Type: research
AbstractMultipronged risk management in diabetes has contributed to the recent decline in cardiovascular mortality. Few antihyperglycemic drugs have been conclusively shown to have cardioprotective effects. These include metformin, liraglutide, semaglutide, dulaglutide, and sodium-glucose cotransporter-2 inhibitors. Statins are the cornerstone of treatment for people with established coronary artery disease (CAD) or at risk of CAD. In patients with persistent low-density lipoprotein cholesterol (LDL-C) levels>  70 mg/dL, the addition of ezetimibe or proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibit...
Source: American Journal of Cardiovascular Drugs - Category: Cardiology Source Type: research
Purpose of review Type 2 diabetes is associated with a characteristic dyslipidemia that may exacerbate cardiovascular risk. The causes of, and the effects of new antihyperglycemia medications on, this dyslipidemia, are under investigation. In an unexpected reciprocal manner, lowering LDL-cholesterol with statins slightly increases the risk of diabetes. Here we review the latest findings. Recent findings The inverse relationship between LDL-cholesterol and diabetes has now been confirmed by multiple lines of evidence. This includes clinical trials, genetic instruments using aggregate single nucleotide polymorphisms, as...
Source: Current Opinion in Lipidology - Category: Lipidology Tags: LIPID METABOLISM: Edited by Marit Westerterp and Bart van de Sluis Source Type: research
MRI in patients with cardiac devices, bariatric surgery, statins, the LifeVest wearable defibrillator, and spontaneous coronary dissection are the topics discussed in this week's podcast.theheart.org on Medscape
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Cardiology Commentary Source Type: news
Previous Statin for primary prevention Very high lipid levels of the order of LDL cholesterol above 190 mg/dL calls for usage of statins for primary prevention. High intensity statins can be considered in this scenario as in acute coronary syndrome. When the LDL cholesterol level is between 70-189 mg/dL, primary prevention with moderate intensity statin may be considered if they are diabetic and have significant other risk factors for CAD. It is reasonable to measure SGPT/ALT levels before initiating statins and while on treatment so that values above 3 times the upper limit are not reached. Caution is advised in those abo...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Cardiology Source Type: blogs
AbstractPurposeGiven the lack of evidence of the effect of bariatric surgery (BS) on atherogenic dyslipidemia (AD), which is a characteristic of obese subjects, this study aimed to describe the remission rate of AD 1  year after BS in severely obese patients.Materials and MethodsA non-randomised, prospective cohort study was conducted in patients undergoing laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy with a 1-year follow-up. AD was defined as triglycerides ≥1.71 mmol/l or treatment with fibrates and low high-density lipoprotein (HDL) cholesterol (
Source: Obesity Surgery - Category: Surgery Source Type: research
Bariatric surgeries are considered effective treatments for weight loss and improved diabetes control. Statins increase diabetes onset in prospective clinical trials and many bariatric patients with metabolic disease are concurrently on statins. We retrospectively examined the relationship of statin therapy to weight loss, diabetes mellitus onset and remission, and metabolic outcomes after bariatric surgery. 1575 patients (1231 women) underwent laparoscopic adjustable gastric banding (LAGB, n=1035), Roux-en-Y gastric bypass (RYGB, n=468), or sleeve gastrectomy (SG, n=72) and were categorized as to statin use (n=671 statin ...
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
Publication date: Available online 28 May 2016 Source:Best Practice & Research Clinical Endocrinology & Metabolism Author(s): Auryan Szalat, Ronen Durst, Eran Leitersdorf Glucose-control has a modest beneficial effect on cardiovascular outcomes in patients with type 2 diabetes mellitus. Thus, managing other atherogenic risk factors including hypertriglyceridemia, low HDL-cholesterol and moderately elevated LDL-cholesterol levels with increased small dense LDL-cholesterol fraction, is crucial. Insulin resistance is a key pathophysiologic factor in this population. Treatment starts with lifestyle modifications, ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
More News: Bariatric Surgery | Cardiology | Cholesterol | Heart | Podcasts | Statin Therapy