IJERPH, Vol. 15, Pages 155: Trends in Resistance to Extended-Spectrum Cephalosporins and Carbapenems among Escherichia coli and Klebsiella spp. Isolates in a District in Western India during 2004 –2014
IJERPH, Vol. 15, Pages 155: Trends in Resistance to Extended-Spectrum Cephalosporins and Carbapenems among Escherichia coli and Klebsiella spp. Isolates in a District in Western India during 2004–2014
International Journal of Environmental Research and Public Health doi: 10.3390/ijerph15010155
Authors:
Ingvild Odsbu
Smita Khedkar
Frida Lind
Uday Khedkar
Sandeep Nerkar
Nicola Orsini
Ashok Tamhankar
Cecilia Stålsby Lundborg
Surveillance data on the level of resistant bacteria is needed to inform strategies to reduce the development and spread of antibiotic resistance. The aim of this study was to determine the non-susceptibility trends to extended-spectrum cephalosporins and carbapenems among Escherichia coli and Klebsiella spp. isolates from the district of Nashik in Western India during the period 2004–2014. Antibacterial susceptibility testing of clinical isolates was performed using Kirby-Bauer disc diffusion method to determine inhibitory zone diameters. The change in proportions of non-susceptible bacteria over calendar time was investigated with spline transformations in a logistic regression model. For the extended-spectrum cephalosporins, the proportions of non-susceptible E. coli and Klebsiella spp. isolates were above 78.4% and 84.9% throughout the study period, respectively. E. coli and Klebsiella spp. isolates exhibited carbapenem non-susceptibility levels as high as 76.9% and 84.1% respectively. The proportions of extended-spectrum betal...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Ingvild Odsbu Smita Khedkar Frida Lind Uday Khedkar Sandeep Nerkar Nicola Orsini Ashok Tamhankar Cecilia St ålsby Lundborg Tags: Article Source Type: research
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