Catastrophic Depolymerization of Microtubules Driven by Subunit Shape Change

Soft Matter, 2018, Accepted Manuscript DOI: 10.1039/C7SM02033C, CommunicationJonathan Allen Bollinger, Mark Stevens Microtubules exhibit a dynamic instability between growth and catastrophic depolymerization. GTP-tubulin ([small alpha][small beta]-dimer bound to GTP) self-assembles, but dephosphorylation of GTP- to GDP-tubulin within the tubule results in destabilization. While the... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Soft Matter latest articles - January 17, 2018 Category: Chemistry Authors: Jonathan Allen Bollinger Source Type: research