Analysis of MED12 Mutation in Multiple Uterine Leiomyomas in South Korean patients.

In conclusion, we confirmed the high frequency of the MED12 mutation in uterine leiomyomas of South Korean patients. We also identified various MED12 mutation status in patients with multiple leiomyomas. This suggests that in a given patient, different tumors may have arisen from different cell origins and therefore it is supposed that occurrence of multiple leiomyoma in a single patient may not be caused by intrauterine metastasis or dissemination. PMID: 29333096 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29333096?dopt=Abstract

Source: International Journal of Medical Sciences - January 17, 2018 Category: Biomedical Science Tags: Int J Med Sci Source Type: research