Clinical utility of a STAT3-regulated microRNA-200 family signature with prognostic potential in early gastric cancer.

Conclusions: Collectively, our discovery of a STAT3-regulated, miR-200 family-associated gene signature specific for EGC, with predictive power, provides a molecular rationale to classify and stratify EGC patients for endoscopic treatment.
PMID: 29330205 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - January 12, 2018 Category: Cancer & Oncology Authors: Yu L, Wu D, Gao H, Balic J, Tsykin A, Han TS, Liu YD, Kennedy CL, Li JK, Mao JQ, Tan P, Oshima M, Goodall GJ, Jenkins BJ Tags: Clin Cancer Res Source Type: research