Differences in histological features and PD-L1 expression between sporadic microsatellite instability and Lynch-syndrome-associated disease in Japanese patients with colorectal cancer.

CONCLUSIONS: Therefore, compared with Lynch-syndrome-associated cancers, sporadic MSI cancers are more frequently solid, poorly differentiated medullary cancers that express PD-L1.
PMID: 29327160 [PubMed - as supplied by publisher]

Source: Clinical Colorectal Cancer - January 11, 2018 Category: Cancer & Oncology Authors: Yamada R, Yamaguchi T, Iijima T, Wakaume R, Takao M, Koizumi K, Hishima T, Horiguchi SI Tags: Int J Clin Oncol Source Type: research