The correlation of Evans index with CSF protein levels and ventriculomegaly.

CONCLUSION: There seems to be a significant correlation between EI value, age and Aβ reduction in the CSF. No correlation was found between EI and tau and p-tau proteins in the CSF. This may indicate that Aβ levels in the CSF are affected significantly by ventriculomegaly and not as much by pathophysiological pathways characteristic for each dementia entity. On the other hand, tau and p-tau proteins could possibly play a crucial role in the differential diagnosis of iNPH and other dementia entities, as these proteins cannot be predicted by ventricular enlargement. PMID: 29324921 [PubMed - in process]
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research